Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

The human mouth harbours one of the most diverse microbiomes in the human body,
including viruses, fungi, protozoa, archaea and bacteria. The bacteria are responsible for the …

Gut microbiota is an assortment of microorganisms inhabiting the length and width of the
mammalian gastrointestinal tract. The composition of this microbial community is host …

The ability of ketogenic low‐carbohydrate (CHO) high‐fat (K‐LCHF) diets to enhance
muscle fat oxidation has led to claims that it is the 'future of elite endurance sport'. There is …

Nitric oxide (NO) from endothelial NO synthase importantly contributes to vascular
homeostasis. Reduced NO production or increased scavenging during disease conditions …

The discovery that dietary (inorganic) nitrate has important vascular effects came from the
relatively recent realization of the 'nitrate‐nitrite‐nitric oxide (NO) pathway'. Dietary nitrate …

Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …

Background Dietary nitrate has a controversial role in human health. For over half a century,
the nitrate content of the three major dietary sources–vegetables, meat, and water–has been …