Amino acid networks (AANs) are undirected networks consisting of amino acid residues and
their interactions in three-dimensional protein structures. The analysis of AANs provides …

Traditionally, protein structures have been analysed by the secondary structure architecture
and fold arrangement. An alternative approach that has shown promise is modelling …

Alternative techniques and tools for analyzing biomolecular networks With the recent rapid
advances in molecular biology, high-throughput experimental methods have resulted in …

Network theory is now a method of choice to gain insights in understanding protein structure,
folding and function. In combination with molecular dynamics (MD) simulations, it is an …

Motivation Non-coding RNA molecules play essential roles by interacting with other
molecules to perform various biological functions. However, it is difficult to determine RNA …

β-lactamases are enzymes produced by bacteria to hydrolyze β-lactam antibiotics as a
common mechanism of resistance. Evolution in such enzymes has been rendering a wide …

The affinity and specificity of protein-ligand interactions are influenced by energetic crosstalk
within the protein domain. However, the molecular details of such intradomain allostery are …

In this study, we evaluated the copy number variation in the genomes of two groups of
Beichuan-white goat populations with large differences in litter size by F ST method, and …

Protein structure and protein function should be related, yet the nature of this relationship
remains unsolved. Map** the critical residues for protein function with protein structure …

The integration of structural and network-based systems biology is paramount for the
improved understanding of how the proteins interact to modulate the behavior of complex …