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[HTML][HTML] Anabolic therapies in osteoporosis and bone regeneration
Osteoporosis represents the most common bone disease worldwide and results in a
significantly increased fracture risk. Extrinsic and intrinsic factors implicated in the …
significantly increased fracture risk. Extrinsic and intrinsic factors implicated in the …
Systemic therapy of MSCs in bone regeneration: a systematic review and meta-analysis
J Fu, Y Wang, Y Jiang, J Du, J Xu, Y Liu - Stem cell research & therapy, 2021 - Springer
Objectives Over the past decades, many studies focused on mesenchymal stem cells
(MSCs) therapy for bone regeneration. Due to the efficiency of topical application has been …
(MSCs) therapy for bone regeneration. Due to the efficiency of topical application has been …
Innovative linker strategies for tumor‐targeted drug conjugates
The covalent conjugation of potent cytotoxic agents to either macromolecular carriers or
small molecules represents a well‐known approach to increase the therapeutic index of …
small molecules represents a well‐known approach to increase the therapeutic index of …
Fluorescent self‐threaded peptide probes for biological imaging
A general synthetic method creates a new class of covalently connected, self‐threaded,
fluorescent molecular probes with figure‐eight topology, an encapsulated deep‐red …
fluorescent molecular probes with figure‐eight topology, an encapsulated deep‐red …
[HTML][HTML] Biomimicking design of artificial periosteum for promoting bone healing
Background Periosteum is a vascularized tissue membrane covering the bone surface and
plays a decisive role in bone reconstruction process after fracture. Various artificial …
plays a decisive role in bone reconstruction process after fracture. Various artificial …
Osteoporosis: Current and emerging therapies targeted to immunological checkpoints
M De Martinis, MM Sirufo… - Current medicinal …, 2020 - ingentaconnect.com
Osteoporosis is a skeletal pathology characterized by compromised bone strength leading
to increased risk of fracture, mainly the spine and hip fractures. Osteoporosis affects more …
to increased risk of fracture, mainly the spine and hip fractures. Osteoporosis affects more …
Nanocomposites drug delivery systems for the healing of bone fractures
The skeletal system is fundamental for the structure and support of the body consisting of
bones, cartilage, and connective tissues. Poor fracture healing is a chief clinical problem …
bones, cartilage, and connective tissues. Poor fracture healing is a chief clinical problem …
Methods to accelerate fracture healing–a narrative review from a clinical perspective
Bone regeneration is a complex pathophysiological process determined by molecular,
cellular, and biomechanical factors, including immune cells and growth factors. Fracture …
cellular, and biomechanical factors, including immune cells and growth factors. Fracture …
Stimulation of fracture mineralization by salt-inducible kinase inhibitors
Introduction Over 6.8 million fractures occur annually in the US, with 10% experiencing
delayed-or non-union. Anabolic therapeutics like PTH analogs stimulate fracture repair, and …
delayed-or non-union. Anabolic therapeutics like PTH analogs stimulate fracture repair, and …
Bone-targeting systems to systemically deliver therapeutics to bone fractures for accelerated healing
Abstract Purpose of Review Compared with the current standard of implanting bone
anabolics for fracture repair, bone fracture-targeted anabolics would be more effective, less …
anabolics for fracture repair, bone fracture-targeted anabolics would be more effective, less …