Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Effects of different exercise training modes on muscle strength and physical performance in older people with sarcopenia: a systematic review and meta-analysis

L Lu, L Mao, Y Feng, BE Ainsworth, Y Liu, N Chen - BMC geriatrics, 2021 - Springer
Objective We conducted a systematic review and meta-analysis to clarify the effects of
different exercise modes (resistance training [RT], whole body vibration training [WBVT], and …

Exercise therapy for people with sarcopenic obesity: myokines and adipokines as effective actors

H Alizadeh Pahlavani - Frontiers in endocrinology, 2022 - frontiersin.org
Sarcopenic obesity is defined as a multifactorial disease in aging with decreased body
muscle, decreased muscle strength, decreased independence, increased fat mass, due to …

Biochemical markers of musculoskeletal health and aging to be assessed in clinical trials of drugs aiming at the treatment of sarcopenia: consensus paper from an …

A Ladang, C Beaudart, JY Reginster… - Calcified Tissue …, 2023 - Springer
In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

Myostatin as a biomarker of muscle wasting and other pathologies-state of the art and knowledge gaps

J Baczek, M Silkiewicz, ZB Wojszel - Nutrients, 2020 - mdpi.com
Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life,
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …

Myostatin: Basic biology to clinical application

P Esposito, D Picciotto, Y Battaglia, F Costigliolo… - Advances in clinical …, 2022 - Elsevier
Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …

Is moderate resistance training adequate for older adults with sarcopenia? A systematic review and network meta-analysis of RCTs

YC Chen, WC Chen, CW Liu, WY Huang, IC Lu… - European Review of …, 2023 - Springer
Background Resistance training (RT) and nutritional supplementation are recommended for
the management of sarcopenia in older adults. However, optimal RT intensity for the …

Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in …

C Griffen, M Duncan, J Hattersley, MO Weickert… - Experimental …, 2022 - Elsevier
Purpose To determine the individual and combined effects of 12 weeks of resistance
exercise (RE) and whey protein supplementation on skeletal muscle strength (primary …

Ketogenic diets, physical activity and body composition: a review

D Ashtary-Larky, R Bagheri, H Bavi, JS Baker… - British Journal of …, 2022 - cambridge.org
Obesity remains a serious relevant public health concern throughout the world despite
related countermeasures being well understood (ie mainly physical activity and an adjusted …

Exercise programs combined with diet supplementation improve body composition and physical function in older adults with sarcopenia: a systematic review

MA Hernández-Lepe, MI Miranda-Gil… - Nutrients, 2023 - mdpi.com
Sarcopenia is a progressive and frequent syndrome among older adults highly related to
physical inactivity and malnutrition. Nowadays, it is considered a pathology that triggers …