The role of the CCN family of proteins in female reproduction

E Winterhager, A Gellhaus - Cellular and Molecular Life Sciences, 2014 - Springer
The CCN family of proteins consists of six high homologous matricellular proteins which act
predominantly by binding to heparin sulphate proteoglycan and a variety of integrins …

Early detection of maternal risk for preeclampsia

B Mikat, A Gellhaus, N Wagner, C Birdir… - International …, 2012 - Wiley Online Library
Preeclampsia is one of the leading causes of maternal and fetal morbidity and mortality.
New molecular insights offer new possibilities of early diagnosis of elevated maternal risk …

Circulating angiogenic factors and their association with birth outcomes in preeclampsia

AV Kulkarni, SS Mehendale, HR Yadav, AS Kilari… - Hypertension …, 2010 - nature.com
This study was designed to test the hypothesis that altered angiogenic factors together with
increased oxidative stress and reduced docosahexaenoic acid (DHA) levels may be …

Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1α and transforming-growth factor-β3 in the human trophoblast

N Wolf, W Yang, CE Dunk, I Gashaw, SJ Lye… - …, 2010 - academic.oup.com
It is known that a hypoxic environment is critical for trophoblast migration and invasion and is
fundamental for appropriate placental perfusion. Because cysteine-rich 61 (CYR61, CCN1) …

Иммунопатогенетические механизмы формирования плацентарной недостаточности и ранних репродуктивных потерь

ИА Газиева - 2014 - elibrary.ru
Научно обоснована концепция реализации прерывания беременности в первом
триместре и развития плацентарной недостаточности с позиций нарушения регуляции …

Роль факторов роста в развитии плацентарной недостаточности и преэклампсии

АВ Мурашко, ШМ Магомедова - Архив акушерства и гинекологии …, 2015 - cyberleninka.ru
Цель исследования определить роль инсулиноподобного фактора роста-1 (ИФР-1) и
плацентарного лактогена (ПЛ) в развитии плацентарной недостаточности и …

Placental growth factor: a predictive marker for preeclampsia?

M Schmidt, C Dogan, C Birdir, U Kuhn… - Gynäkologisch …, 2009 - karger.com
Background: An imbalance between angiogenic and antiangiogenic factors plays a
fundamental role in the pathogenesis of preeclampsia. Serum levels of placental growth …

Gene expression in chorionic villous samples at 11 weeks of gestation in women who develop preeclampsia later in pregnancy: implications for screening

A Farina, D Morano, D Arcelli… - … in Affiliation With the …, 2009 - Wiley Online Library
Objectives To determine the gene expression profile in chorionic villous samples (CVS) of
women destined to develop preeclampsia. Method cDNA microarray technology was …

[PDF][PDF] Современные аспекты этиологии и патогенеза плацентарной недостаточности

ШМ Магомедова - Акушерство и гинекология, 2013 - vestnikdgma.ru
Резюме Проведен литературный обзор современных аспектов этиологии и патогенеза
плацентарной недостаточности и преэклампсии. Установлено, что проблемы ранней …

Determination of sFlt-1: angiogenic factor complex

G Bashirians, D Byrne, S Groulx, S Jackson… - US Patent …, 2014 - Google Patents
Fetal Interface'J Soc Gynecol Investig, Jan./Feb. 2002, vol. 9, No. 1 (Supplement), p. 80A,
Abstract# 45. Eriksson, A. et al.“Placenta growth-factor-1 antagonizes VEGF induced …