[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq
Spatial resolution of the T cell repertoire is essential for deciphering cancer-associated
immune dysfunction. Current spatially resolved transcriptomic technologies are unable to …
immune dysfunction. Current spatially resolved transcriptomic technologies are unable to …
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
Oxford Nanopore (ONT) is a leading long-read technology which has been revolutionizing
transcriptome analysis through its capacity to sequence the majority of transcripts from end …
transcriptome analysis through its capacity to sequence the majority of transcripts from end …
Enhancing novel isoform discovery: leveraging nanopore long-read sequencing and machine learning approaches
K Santucci, Y Cheng, SM Xu… - Briefings in Functional …, 2024 - academic.oup.com
Long-read sequencing technologies can capture entire RNA transcripts in a single
sequencing read, reducing the ambiguity in constructing and quantifying transcript models in …
sequencing read, reducing the ambiguity in constructing and quantifying transcript models in …
Porechop_ABI: discovering unknown adapters in Oxford Nanopore Technology sequencing reads for downstream trimming
Abstract Motivation Oxford Nanopore Technologies (ONT) sequencing has become very
popular over the past few years and offers a cost-effective solution for many genomic and …
popular over the past few years and offers a cost-effective solution for many genomic and …
Reference-free assembly of long-read transcriptome sequencing data with RNA-Bloom2
Long-read sequencing technologies have improved significantly since their emergence.
Their read lengths, potentially spanning entire transcripts, is advantageous for …
Their read lengths, potentially spanning entire transcripts, is advantageous for …
Hepatitis B virus serum RNA transcript isoform composition and proportion in chronic hepatitis B patients by nanopore long-read sequencing
Introduction Serum hepatitis B virus (HBV) RNA is a promising new biomarker to manage
and predict clinical outcomes of chronic hepatitis B (CHB) infection. However, the HBV …
and predict clinical outcomes of chronic hepatitis B (CHB) infection. However, the HBV …
isONform: reference-free transcriptome reconstruction from Oxford Nanopore data
Motivation With advances in long-read transcriptome sequencing, we can now fully
sequence transcripts, which greatly improves our ability to study transcription processes. A …
sequence transcripts, which greatly improves our ability to study transcription processes. A …
Coordinated wound responses in a regenerative animal-algal holobiont
Animal regeneration involves coordinated responses across cell types throughout the
animal body. In endosymbiotic animals, whether and how symbionts react to host injury and …
animal body. In endosymbiotic animals, whether and how symbionts react to host injury and …
Freddie: annotation-independent detection and discovery of transcriptomic alternative splicing isoforms using long-read sequencing
Alternative splicing (AS) is an important mechanism in the development of many cancers, as
novel or aberrant AS patterns play an important role as an independent onco-driver. In …
novel or aberrant AS patterns play an important role as an independent onco-driver. In …