Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives

R Sun, J **ang, Q Zhou, Y Piao, J Tang, S Shao… - Advanced drug delivery …, 2022 - Elsevier
Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …

Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Nanoparticle‐based photothermal therapy for breast cancer noninvasive treatment

Y **ong, Y Rao, J Hu, Z Luo, C Chen - Advanced materials, 2023 - Wiley Online Library
Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

Chemical and biophysical signatures of the protein corona in nanomedicine

J Ren, N Andrikopoulos, K Velonia… - Journal of the …, 2022 - ACS Publications
An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Rational design of platinum–bismuth sulfide schottky heterostructure for sonocatalysis‐mediated hydrogen therapy

M Yuan, S Liang, L Yang, F Li, B Liu, C Yang… - Advanced …, 2023 - Wiley Online Library
Conventional sonodynamic therapy is unavoidably limited by the tumor microenvironment,
although many sonosensitizers have been developed to improve them to a certain extent …

Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

SB Fournier, JN D'Errico, DS Adler, S Kollontzi… - Particle and Fibre …, 2020 - Springer
Abstract Background Plastic is everywhere. It is used in food packaging, storage containers,
electronics, furniture, clothing, and common single-use disposable items. Microplastic and …

Engineering tumoral vascular leakiness with gold nanoparticles

MI Setyawati, Q Wang, N Ni, JK Tee, K Ariga… - Nature …, 2023 - nature.com
Delivering cancer therapeutics to tumors necessitates their escape from the surrounding
blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer …