Heat-shock proteins in neuroinflammation

B Dukay, B Csoboz, ME Tóth - Frontiers in pharmacology, 2019 - frontiersin.org
The heat-shock response, one of the main pro-survival mechanisms of a living organism,
has evolved as the biochemical response of cells to cope with heat stress. The most well …

[HTML][HTML] Role of a heat shock transcription factor and the major heat shock protein Hsp70 in memory formation and neuroprotection

OG Zatsepina, MB Evgen'ev, DG Garbuz - Cells, 2021 - mdpi.com
Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and
universal system for protecting cells and the whole body from various types of stress. Among …

Proteomic Analysis of Cattle Tick Rhipicephalus (Boophilus) microplus Saliva: A Comparison between Partially and Fully Engorged Females

L Tirloni, J Reck, RMS Terra, JR Martins, A Mulenga… - PloS one, 2014 - journals.plos.org
The cattle tick Rhipicephalus (Boophilus) microplus is one of the most harmful parasites
affecting bovines. Similarly to other hematophagous ectoparasites, R. microplus saliva …

The many faces of C/EBPδ and their relevance for inflammation and cancer

K Balamurugan, E Sterneck - International journal of biological …, 2013 - pmc.ncbi.nlm.nih.gov
The CCAAT/enhancer binding protein delta (CEBPD, C/EBPδ) is a transcription factor that
modulates many biological processes including cell differentiation, motility, growth arrest …

Melatonin receptor agonist protects against acute lung injury induced by ventilator through up-regulation of IL-10 production

GC Wu, CK Peng, WI Liao, HP Pao, KL Huang… - Respiratory …, 2020 - Springer
Background It is well known that ventilation with high volume or pressure may damage
healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal …

IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70)

RL Lopes, TJ Borges, RF Zanin, C Bonorino - Cytokine, 2016 - Elsevier
Macrophages are key cells in the innate immune system. They phagocytose pathogens and
cellular debris, promote inflammation, and have important roles in tumor immunity …

Emerging role of nitric oxide and heat shock proteins in insulin resistance

MN Molina, L Ferder, W Manucha - Current hypertension reports, 2016 - Springer
Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic
syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and …

The future of biology in driving the field of hyperthermia

MW Dewhirst, CT Lee, KA Ashcraft - International Journal of …, 2016 - Taylor & Francis
Abstract In 2011 Hanahan and Weinberg updated their well-established paper 'The
hallmarks of cancer'. The rationale for that review and its predecessor was to produce a …

Beta amyloid, tau protein, and neuroinflammation: an attempt to integrate different hypotheses of Alzheimer's disease pathogenesis

DG Garbuz, OG Zatsepina, MB Evgen'ev - Molecular Biology, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease that inevitably results in dementia
and death. Currently, there are no pathogenetically grounded methods for the prevention …

Coronavirus infection (SARS-CoV-2) in obesity and diabetes comorbidities: is heat shock response determinant for the disease complications?

M Krause, F Gerchman, R Friedman - Diabetology & metabolic syndrome, 2020 - Springer
Chronic inflammation is involved in the pathogenesis of several metabolic diseases, such as
obesity and type 2 diabetes mellitus (T2DM). With the recent worldwide outbreak of …