Over the past decade, cross-linking mass spectrometry (CLMS) has developed into a robust
and flexible tool that provides medium-resolution structural information. CLMS data provide …

Chemical cross-linking of reactive groups in native proteins and protein complexes in
combination with the identification of cross-linked sites by mass spectrometry has been in …

Protein chemical cross-linking and mass spectrometry enable the analysis of protein–protein
interactions and protein topologies; however, complicated cross-linked peptide spectra …

Mass spectrometry (MS) is becoming increasingly popular in the field of structural biology for
analyzing protein three‐dimensional‐structures and for map** protein–protein …

Most protein complexes are inaccessible to high resolution structural analysis. We report the
results of a combined approach of cross-linking, mass spectrometry, and bioinformatics to …

Chemical cross-linking coupled with mass spectrometry, an emerging approach for protein
topology and interaction studies, has gained increasing interest in the past few years. A …

We present results from a novel strategy that enables concurrent identification of protein-
protein interactions and topologies in living cells without specific antibodies or genetic …

The nosocomial pathogen Acinetobacter baumannii is a frequent cause of hospital-acquired
infections worldwide and is a challenge for treatment due to its evolved resistance to …

Protein interaction topologies are critical determinants of biological function. Large-scale or
proteome-wide measurements of protein interaction topologies in cells currently pose an …

Functional Proteomics aims to the identification of in vivo protein-protein interaction (PPI) in
order to piece together protein complexes, and therefore, cell pathways involved in …