Reconstructing genome-scale metabolic models with merlin

O Dias, M Rocha, EC Ferreira, I Rocha - Nucleic acids research, 2015 - academic.oup.com
Abstract The Metabolic Models Reconstruction Using Genome-Scale Information (merlin)
tool is a user-friendly Java application that aids the reconstruction of genome-scale …

A review of methods for the reconstruction and analysis of integrated genome-scale models of metabolism and regulation

F Cruz, JP Faria, M Rocha, I Rocha… - Biochemical Society …, 2020 - portlandpress.com
The current survey aims to describe the main methodologies for extending the
reconstruction and analysis of genome-scale metabolic models and phenotype simulation …

iOD907, the first genome‐scale metabolic model for the milk yeast Kluyveromyces lactis

O Dias, R Pereira, AK Gombert… - Biotechnology …, 2014 - Wiley Online Library
We describe here the first genome‐scale metabolic model of Kluyveromyces lactis, iOD907.
It is partially compartmentalized (four compartments), composed of 1867 reactions and 1476 …

The first multi-tissue genome-scale metabolic model of a woody plant highlights suberin biosynthesis pathways in Quercus suber

E Cunha, M Silva, I Chaves, H Demirci… - PLoS Computational …, 2023 - journals.plos.org
Over the last decade, genome-scale metabolic models have been increasingly used to study
plant metabolic behaviour at the tissue and multi-tissue level under different environmental …

iDS372, a Phenotypically Reconciled Model for the Metabolism of Streptococcus pneumoniae Strain R6

O Dias, J Saraiva, C Faria, M Ramirez, F Pinto… - Frontiers in …, 2019 - frontiersin.org
A high-quality GSM model for Streptococcus pneumoniae R6 model strain (iDS372),
comprising 372 genes and 529 reactions, was developed. The construction of this model …

Reconstructing high-quality large-scale metabolic models with merlin

O Dias, M Rocha, EC Ferreira, I Rocha - … Network Reconstruction and …, 2018 - Springer
Here, the basic principles of reconstructing genome-scale metabolic models with merlin are
described. This tool covers the basic stages of this process, providing several tools that …

BioISO: an objective-oriented application for assisting the curation of genome-scale metabolic models

F Cruz, J Capela, EC Ferreira… - … /ACM transactions on …, 2024 - ieeexplore.ieee.org
As the reconstruction of Genome-Scale Metabolic Models (GEMs) becomes standard
practice in systems biology, the number of organisms having at least one metabolic model is …

M3L: Exploring Synergies Between Metabolic Modelling and Machine Learning for Studying Plants

MSC Sampaio - 2024 - search.proquest.com
Vitis vinifera (videira) é uma das principais árvores de fruto do mundo, sendo amplamente
cultivada e comercializada, principalmente para produção de vinho. Como a qualidade do …

[PDF][PDF] iEC7871 quercus suber model: the first multi-tissue diel cycle genome-scale metabolic model of a woody tree

E Cunha, M Silva, I Chaves, H Demirci, D Lagoa… - bioRxiv, 2021 - scholar.archive.org
In the last decade, genome-scale metabolic models have been increasingly used to study
plant metabolic behaviour at the tissue and multi-tissue level in different environmental …

Exploring Xylella fastidiosa's Metabolic Traits Using a GSM Model of the Phytopathogenic Bacterium

A Oliveira, E Cunha, M Silva, C Faria, O Dias - … Conference on Practical …, 2022 - Springer
Xylella fastidiosa is a gram-negative phytopathogenic bacterium able to infect over 500 plant
species, with devastating consequences for agricultural and forest-based economies. In the …