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Emerging clinical relevance of microbiome in cancer: promising biomarkers and therapeutic targets
JH Dai, XR Tan, H Qiao, N Liu - Protein & Cell, 2024 - academic.oup.com
The profound influence of microbiota in cancer initiation and progression has been under
the spotlight for years, leading to numerous researches on cancer microbiome entering …
the spotlight for years, leading to numerous researches on cancer microbiome entering …
Long-distance microbial mechanisms impacting cancer immunosurveillance
The intestinal microbiota determines immune responses against extraintestinal antigens,
including tumor-associated antigens. Indeed, depletion or gross perturbation of the …
including tumor-associated antigens. Indeed, depletion or gross perturbation of the …
Programmed nanocloak of commensal bacteria-derived nanovesicles amplify strong immunoreactivity against tumor growth and metastatic progression
Recent discoveries in commensal microbiota demonstrate the great promise of intratumoral
bacteria as attractive molecular targets of tumors in improving cancer treatment. However …
bacteria as attractive molecular targets of tumors in improving cancer treatment. However …
Ultrasound‐activated probiotics vesicles coating for titanium implant infections through bacterial cuproptosis‐like death and immunoregulation
Implant‐associated infections (IAIs) are the main cause of prosthetic implant failure.
Bacterial biofilms prevent antibiotic penetration, and the unique metabolic conditions in …
Bacterial biofilms prevent antibiotic penetration, and the unique metabolic conditions in …
Decomposable nanoagonists enable NIR‐elicited cGAS‐STING activation for tandem‐amplified photodynamic‐metalloimmunotherapy
X Guo, P Tu, X Wang, C Du, W Jiang, X Qiu… - Advanced …, 2024 - Wiley Online Library
Activation of the cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)
pathway has emerged as an efficient strategy to improve the therapeutic outcomes of …
pathway has emerged as an efficient strategy to improve the therapeutic outcomes of …
Orally administrated hydrogel harnessing intratumoral microbiome and microbiota-related immune responses for potentiated colorectal cancer treatment
L Li, S He, B Liao, M Wang, H Lin, B Hu, X Lan, Z Shu… - Research, 2024 - spj.science.org
The intestinal and intratumoral microbiota are closely associated with tumor progression and
response to antitumor treatments. The antibacterial or tumor microenvironment (TME) …
response to antitumor treatments. The antibacterial or tumor microenvironment (TME) …
Fusobacterium nucleatum carcinogenesis and drug delivery interventions
Z Chen, L Huang - Advanced Drug Delivery Reviews, 2024 - Elsevier
The microbiome has emerged as a significant biomarker and modulator in cancer
development and treatment response. Recent research highlights the notable role of …
development and treatment response. Recent research highlights the notable role of …
Novel strategies for modulating the gut microbiome for cancer therapy
Recent advancements in genomics, transcriptomics, and metabolomics have significantly
advanced our understanding of the human gut microbiome and its impact on the efficacy …
advanced our understanding of the human gut microbiome and its impact on the efficacy …
Liposomes-enabled cancer chemoimmunotherapy
L Zhang, J Shi, MH Zhu, Y Huang, Q Lu, P Sun… - Biomaterials, 2024 - Elsevier
Chemoimmunotherapy is an emerging paradigm in the clinic for treating several malignant
diseases, such as non-small cell lung cancer, breast cancer, and large B-cell lymphoma …
diseases, such as non-small cell lung cancer, breast cancer, and large B-cell lymphoma …
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death
Necroptotic immunogenic cell death (ICD) can activate the human immune system to treat
the metastasis and recurrence of triple-negative breast cancer (TNBC). However …
the metastasis and recurrence of triple-negative breast cancer (TNBC). However …