Envenomations by Bothrops asper are often associated with complex and severe local
pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and …

Snakebite envenoming represents a major health problem in tropical and subtropical
countries. Considering the elevated number of accidents and high morbidity and mortality …

There is now wide acceptance of the concept that the similarity between many acute
infectious diseases, be they viral, bacterial, or parasitic in origin, is caused by the …

There is a broad clinical spectrum of renal involvement in snakebite. Besides the local and
systemic symptoms, clinical renal manifestations vary from mild proteinuria, haematuria …

The therapy of snakebite envenomation has been based on the parenteral administration of
animal-derived antivenoms. Despite the success of this treatment at reducing the impact of …

Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

Moderate and severe envenomations by the snake Bothrops asper provoke systemic
alterations, such as systemic bleeding, coagulopathy, hypovolemia, hemodynamic instability …

Snake venom metalloproteinases (SVMPs) are widely distributed in snake venoms and play
important roles in hemostatic disorders and local tissue damage that follows snakebite. The …

Venoms are products of specialized glands and serve many living organisms to immobilize
and kill prey, start digestive processes and act as a defense mechanism. Venoms affect …

The inflammatory events induced in the peritoneal cavity of mice by two PLA2s isolated from
Bothrops asper snake venom were investigated. MT-III, an Asp-49 catalytically active …