Bacillus subtilis, a swiss army knife in science and biotechnology

J Stülke, A Grüppen, M Bramkamp… - Journal of …, 2023 - journals.asm.org
ABSTRACT Next to Escherichia coli, Bacillus subtilis is the most studied and best
understood organism that also serves as a model for many important pathogens. Due to its …

The state of the art in the analysis of two-dimensional gel electrophoresis images

M Berth, FM Moser, M Kolbe, J Bernhardt - Applied microbiology and …, 2007 - Springer
Software-based image analysis is a crucial step in the biological interpretation of two-
dimensional gel electrophoresis experiments. Recent significant advances in image …

A comprehensive proteome map of growing Bacillus subtilis cells

C Eymann, A Dreisbach, D Albrecht, J Bernhardt… - …, 2004 - Wiley Online Library
The proteome of growing cells of Bacillus subtilis was analyzed in order to provide the basis
for its application in microbial physiology. DNA arrays were used to calculate the number of …

Characterization of the E. coli proteome and its modifications during growth and ethanol stress

B Soufi, K Krug, A Harst, B Macek - Frontiers in microbiology, 2015 - frontiersin.org
We set out to provide a resource to the microbiology community especially with respect to
systems biology based endeavors. To this end, we generated a comprehensive dataset …

Systems-wide temporal proteomic profiling in glucose-starved Bacillus subtilis

A Otto, J Bernhardt, H Meyer, M Schaffer… - Nature …, 2010 - nature.com
Functional genomics of the Gram-positive model organism Bacillus subtilis reveals valuable
insights into basic concepts of cell physiology. In this study, we monitor temporal changes in …

Metabolic reprogramming and longevity in quiescence

J Dworkin, CS Harwood - Annual Review of Microbiology, 2022 - annualreviews.org
Since Jacques Monod's foundational work in the 1940s, investigators studying bacterial
physiology have largely (but not exclusively) focused on the exponential phase of bacterial …

Promoter Screening from Bacillus subtilis in Various Conditions Hunting for Synthetic Biology and Industrial Applications

Y Song, JM Nikoloff, G Fu, J Chen, Q Li, N **e… - PloS one, 2016 - journals.plos.org
The use of Bacillus subtilis in synthetic biology and metabolic engineering is highly
desirable to take advantage of the unique metabolic pathways present in this organism. To …

Effects of RelA on Key Virulence Properties of Planktonic and Biofilm Populations of Streptococcus mutans

JAC Lemos, TA Brown Jr, RA Burne - Infection and immunity, 2004 - journals.asm.org
Streptococcus mutans is a biofilm-forming bacterium that is adapted to tolerate rapid and
dramatic fluctuations in nutrient availability, carbohydrate source, and pH in its natural …

Global Dynamics of the Escherichia coli Proteome and Phosphoproteome During Growth in Minimal Medium

NC Soares, P Spat, K Krug… - Journal of proteome …, 2013 - ACS Publications
Recent phosphoproteomics studies have generated relatively large data sets of bacterial
proteins phosphorylated on serine, threonine, and tyrosine, implicating this type of …

Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi‐omics perspective

M Kohlstedt, PK Sappa, H Meyer… - Environmental …, 2014 - Wiley Online Library
The Gram‐positive bacterium B acillus subtilis encounters nutrient limitations and osmotic
stress in its natural soil ecosystem. To ensure survival and sustain growth, highly integrated …