[HTML][HTML] Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

RV Iozzo, L Schaefer - Matrix biology, 2015 - Elsevier
We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

The leucine-rich repeat as a protein recognition motif

B Kobe, AV Kajava - Current opinion in structural biology, 2001 - Elsevier
Leucine-rich repeats (LRRs) are 20–29-residue sequence motifs present in a number of
proteins with diverse functions. The primary function of these motifs appears to be to provide …

Matrix proteoglycans: from molecular design to cellular function

RV Iozzo - Annual review of biochemistry, 1998 - annualreviews.org
The proteoglycan superfamily now contains more than 30 full-time molecules that fulfill a
variety of biological functions. Proteoglycans act as tissue organizers, influence cell growth …

[BOOK][B] Understanding voice problems: A physiological perspective for diagnosis and treatment

JK Casper, R Leonard - 2006 - books.google.com
Now in its Third Edition, this book emphasizes the physiological perspective of voice
disorders—and the behavioral and emotional factors that can influence these changes …

Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance

K Brose, KS Bland, KH Wang, D Arnott, W Henzel… - Cell, 1999 - cell.com
Extending axons in the develo** nervous system are guided in part by repulsive cues.
Genetic analysis in Drosophila, reported in a companion to this paper, identifies the Slit …

Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics

NK Karamanos, Z Piperigkou, AD Theocharis… - Chemical …, 2018 - ACS Publications
The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

RV Iozzo, RD Sanderson - Journal of cellular and molecular …, 2011 - Wiley Online Library
Introduction• Perlecan: a pro‐angiogenic proteoglycan• Endorepellin, a C‐terminal fragment
of perlecan with anti‐angiogenic activity• Syndecans in cancer biology• Glypicans and the …

Myocardial extracellular matrix: an ever-changing and diverse entity

M Rienks, AP Papageorgiou… - Circulation …, 2014 - Am Heart Assoc
The cardiac extracellular matrix (ECM) is a complex architectural network consisting of
structural and nonstructural proteins, creating strength and plasticity. The nonstructural …

The sclera and myopia

JAS Rada, S Shelton, TT Norton - Experimental eye research, 2006 - Elsevier
Myopia is a very common ocular problem, affecting perhaps one billion people worldwide.
Most myopia is produced by lengthening of the vitreous chamber of the ocular globe. High …

Altered wound healing in mice lacking a functional osteopontin gene (spp1).

L Liaw, DE Birk, CB Ballas, JS Whitsitt… - The Journal of …, 1998 - Am Soc Clin Investig
Osteopontin (OPN) is an arginine-glycine-aspartate (RGD)-containing glycoprotein encoded
by the gene secreted phosphoprotein 1 (spp1). spp1 is expressed during embryogenesis …