Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

JR Naglik, SJ Challacombe, B Hube - Microbiology and molecular …, 2003 - Am Soc Microbiol
Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Candida albicans: A molecular revolution built on lessons from budding yeast

J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

G Butler, MD Rasmussen, MF Lin, MAS Santos… - Nature, 2009 - nature.com
Candida species are the most common cause of opportunistic fungal infection worldwide.
Here we report the genome sequences of six Candida species and compare these and …

The diploid genome sequence of Candida albicans

T Jones, NA Federspiel, H Chibana… - Proceedings of the …, 2004 - National Acad Sciences
We present the diploid genome sequence of the fungal pathogen Candida albicans.
Because C. albicans has no known haploid or homozygous form, sequencing was …

White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating

MG Miller, AD Johnson - Cell, 2002 - cell.com
Discovered over a decade ago, white-opaque switching in the human fungal pathogen
Candida albicans is an alternation between two quasistable, heritable transcriptional states …

Natural history and evolutionary principles of gene duplication in fungi

I Wapinski, A Pfeffer, N Friedman, A Regev - Nature, 2007 - nature.com
Gene duplication and loss is a powerful source of functional innovation. However, the
general principles that govern this process are still largely unknown. With the growing …

A fungal phylogeny based on 42 complete genomes derived from supertree and combined gene analysis

DA Fitzpatrick, ME Logue, JE Stajich, G Butler - BMC evolutionary biology, 2006 - Springer
Background To date, most fungal phylogenies have been derived from single gene
comparisons, or from concatenated alignments of a small number of genes. The increase in …

Expandable and reversible copy number amplification drives rapid adaptation to antifungal drugs

RT Todd, A Selmecki - Elife, 2020 - elifesciences.org
Previously, we identified long repeat sequences that are frequently associated with genome
rearrangements, including copy number variation (CNV), in many diverse isolates of the …

Transcription Profiling of Candida albicans Cells Undergoing the Yeast-to-Hyphal Transition

A Nantel, D Dignard, C Bachewich… - Molecular biology of …, 2002 - Am Soc Cell Biol
The ability of the pathogenic fungus Candida albicans to switch from a yeast to a hyphal
morphology in response to external signals is implicated in its pathogenicity. We used glass …

[HTML][HTML] Completion of a parasexual cycle in Candida albicans by induced chromosome loss in tetraploid strains

RJ Bennett, AD Johnson - The EMBO journal, 2003 - embopress.org
The human pathogenic fungus Candida albicans has traditionally been classified as a
diploid, asexual organism. However, mating‐competent forms of the organism were recently …