Global impacts of western diet and its effects on metabolism and health: A narrative review

VJ Clemente-Suárez, AI Beltrán-Velasco… - Nutrients, 2023 - mdpi.com
The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged
foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried …

Gut microbiota in overweight and obesity: crosstalk with adipose tissue

PD Cani, M Van Hul - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Overweight and obesity are characterized by excessive fat mass accumulation produced
when energy intake exceeds energy expenditure. One plausible way to control energy …

New insights and potential therapeutic interventions in metabolic diseases

VJ Clemente-Suárez, A Martín-Rodríguez… - International journal of …, 2023 - mdpi.com
Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …

Unraveling adipose tissue dysfunction: molecular mechanisms, novel biomarkers, and therapeutic targets for liver fat deposition

M Lopez-Yus, C Hörndler, S Borlan, V Bernal-Monterde… - Cells, 2024 - mdpi.com
Adipose tissue (AT), once considered a mere fat storage organ, is now recognized as a
dynamic and complex entity crucial for regulating human physiology, including metabolic …

[HTML][HTML] Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Obesity and leukemia: biological mechanisms, perspectives, and challenges

D Tsilingiris, NG Vallianou, N Spyrou, D Kounatidis… - Current obesity …, 2024 - Springer
Abstract Purpose of Review To examine the epidemiological data on obesity and leukemia;
evaluate the effect of obesity on leukemia outcomes in childhood acute lymphoblastic …

[HTML][HTML] Adipokines and Cardiometabolic Heart Failure with Preserved Ejection Fraction: A State-of-the-Art Review

N Theodorakis, M Kreouzi, C Hitas, D Anagnostou… - Diagnostics, 2024 - mdpi.com
Background: Cardiometabolic heart failure with preserved ejection fraction (HFpEF) is
largely driven by obesity-related factors, including adipokines and bioactive peptides …

Microbiota implications in endocrine-related diseases: from development to novel therapeutic approaches

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2024 - mdpi.com
This comprehensive review article delves into the critical role of the human microbiota in the
development and management of endocrine-related diseases. We explore the complex …

Behavioral lifestyle interventions for weight loss in overweight or obese patients with type 2 diabetes: a systematic review of the literature

S Gostoli, G Raimondi, AP Popa, M Giovannini… - Current Obesity …, 2024 - Springer
Abstract Purpose of Review Around 80–90% of patients with type 2 diabetes mellitus
(T2DM) are overweight or obese, presenting a greater risk for serious health complications …

Cardiometabolic aspects of congenital adrenal hyperplasia

R Krysiak, HL Claahsen-van der Grinten… - Endocrine …, 2025 - academic.oup.com
Abstract Treatment of classic congenital adrenal hyperplasia (CAH) is directed at replacing
deficient hormones and reducing androgen excess. However, even in the era of early …