[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system
B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …
significant amount of research conducted to explore its regulatory role in the physiology and …
Substrate stiffness in nerve cells
W Si, J Gong, X Yang - Brain Science Advances, 2023 - journals.sagepub.com
Recently, substrate stiffness has been involved in the physiology and pathology of the
nervous system. However, the role and function of substrate stiffness remain unclear. Here …
nervous system. However, the role and function of substrate stiffness remain unclear. Here …
Fluid compartments influence elastography of the aging mouse brain
Objective. Elastography of the brain has the potential to reveal subtle but clinically important
changes in the structure and composition as a function of age, disease, and injury …
changes in the structure and composition as a function of age, disease, and injury …
Hippocampus of the APPNL–G–F mouse model of Alzheimer's disease exhibits region-specific tissue softening concomitant with elevated astrogliosis
Widespread neurodegeneration, enlargement of cerebral ventricles, and atrophy of cortical
and hippocampal brain structures are classic hallmarks of Alzheimer's disease (AD) …
and hippocampal brain structures are classic hallmarks of Alzheimer's disease (AD) …
Imaging markers for Normal pressure hydrocephalus: an overview
Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically
presents with Hakim's triad, namely cognitive impairment, gait disturbances, and urinary …
presents with Hakim's triad, namely cognitive impairment, gait disturbances, and urinary …
[HTML][HTML] Mouse Brain Elastography Changes with Sleep/Wake Cycles, Aging, and Alzheimer's Disease
Understanding the physiological processes in aging and how neurodegenerative disorders
affect cognitive function is a high priority for advancing human health. One specific area of …
affect cognitive function is a high priority for advancing human health. One specific area of …
Mechanobiological insight into brain diseases based on mechanosensitive channels: Common mechanisms and clinical potential
B Li, A Zhao, T Tian, X Yang - CNS Neuroscience & …, 2024 - Wiley Online Library
Background As physical signals, mechanical cues regulate the neural cells in the brain. The
mechanosensitive channels (MSCs) perceive the mechanical cues and transduce them by …
mechanosensitive channels (MSCs) perceive the mechanical cues and transduce them by …
Cerebral microcirculatory pulse wave propagation and pulse wave amplitude map** in retrospectively gated MRI
N Kornemann, F Klimeš, AL Kern, L Behrendt… - Scientific Reports, 2023 - nature.com
To analyze cerebral arteriovenous pulse propagation and to generate phase-resolved pulse
amplitude maps from a fast gradient-echo sequence offering flow-related enhancement …
amplitude maps from a fast gradient-echo sequence offering flow-related enhancement …
[HTML][HTML] The (un) known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications
Metabolic syndrome (MetS) has been associated with disruptions in tissue mechanical
homeostasis and inflammatory and metabolic derangements. However, the direct correlation …
homeostasis and inflammatory and metabolic derangements. However, the direct correlation …
Biomechanical perspectives on traumatic brain injury in the elderly: A comprehensive review
Traumatic brain injuries (TBIs) pose a significant health concern among the elderly
population, influenced by age-related physiological changes and the prevalence of …
population, influenced by age-related physiological changes and the prevalence of …