Adjuvant systemic therapy and adjuvant radiation therapy for stage I to IIIA completely resected non–small-cell lung cancers: American Society of Clinical Oncology …

MG Kris, LE Gaspar, JE Chaft, EB Kennedy… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The panel updated the American Society of Clinical Oncology (ASCO) adjuvant
therapy guideline for resected non–small-cell lung cancers. Methods ASCO convened an …

A review of chemotherapy and photodynamic therapy for lung cancer treatment

A El-Hussein, SL Manoto… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Cancer is among the leading causes of mortality and morbidity worldwide. Among the
different types of cancers, lung cancer is considered to be the leading cause of death related …

Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma

H Yang, B Sun, L Fan, W Ma, K Xu, SRR Hall… - …, 2022 - pmc.ncbi.nlm.nih.gov
Rationale: Subsets of patients with early-stage lung adenocarcinoma (LUAD) have a poor
post-surgical course after curative surgery. However, biomarkers stratifying this high-risk …

Survival nomogram for stage IB non-small-cell lung cancer patients, based on the SEER database and an external validation cohort

Z Zuo, G Zhang, P Song, J Yang, S Li, Z Zhong… - Annals of surgical …, 2021 - Springer
Objective This study aimed to construct a nomogram to effectively predict the overall survival
(OS) of patients with stage IB non-small-cell lung cancer (NSCLC). Methods In total, 5513 …

Identification and validation of hypoxia-derived gene signatures to predict clinical outcomes and therapeutic responses in stage I lung adenocarcinoma patients

R Shi, X Bao, K Unger, J Sun, S Lu, F Manapov… - …, 2021 - pmc.ncbi.nlm.nih.gov
Rationale: The current tumour-node-metastasis (TNM) staging system is insufficient for
precise treatment decision-making and accurate survival prediction for patients with stage I …

Association of survival with adjuvant chemotherapy among patients with early-stage non–small cell lung cancer with vs without high-risk clinicopathologic features

R Pathak, SB Goldberg, M Canavan, J Herrin… - JAMA …, 2020 - jamanetwork.com
Importance Tumor size larger than 4 cm is accepted as an indication for adjuvant
chemotherapy in patients with node-negative non–small cell lung cancer (NSCLC) …

Regulation of head and neck squamous cancer stem cells by PI3K and SOX2

SB Keysar, PN Le, B Miller, BC Jackson… - Journal of the …, 2017 - academic.oup.com
Background: Not all breast cancer patients benefit from neoadjuvant or adjuvant therapy,
resulting in considerable undertreatment or overtreatment. New insights into the role of …

[HTML][HTML] Chemotherapy remains an essential element of personalized care for persons with lung cancers

MD Hellmann, BT Li, JE Chaft, MG Kris - Annals of Oncology, 2016 - Elsevier
Molecularly targeted and immunotherapies have improved the care of patients with lung
cancers. These successes have rallied calls to replace or avoid chemotherapy. Yet, even in …

Stereotactic body radiation therapy for non-small cell lung cancer: A review

KM Prezzano, SJ Ma, GM Hermann… - World journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Stereotactic body radiation therapy (SBRT) is the treatment of choice for medically
inoperable patients with early stage non-small cell lung cancer (NSCLC). A literature search …

Adjuvant chemotherapy for high-risk pathologic stage I non-small cell lung cancer

Y Tsutani, K Imai, H Ito, Y Miyata, N Ikeda… - The Annals of Thoracic …, 2022 - Elsevier
Background This study aimed to investigate the efficacy of adjuvant chemotherapy for
pathologic stage I non-small cell lung cancer (NSCLC) with high risk for recurrence …