Stage IV colorectal cancer management and treatment
O Hernandez Dominguez, S Yilmaz… - Journal of Clinical …, 2023 - mdpi.com
(1) Background: Colorectal cancer (CRC) is the third most common cancer and the second
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …
[HTML][HTML] Systemic treatment for metastatic colorectal cancer
W Leowattana, P Leowattana… - World journal of …, 2023 - ncbi.nlm.nih.gov
Significant progress has been achieved in the treatment of metastatic colorectal cancer
(mCRC) patients during the last 20 years. There are currently numerous treatments …
(mCRC) patients during the last 20 years. There are currently numerous treatments …
Repeated centralized multidisciplinary team assessment of resectability, clinical behavior, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO) …
P Osterlund, T Salminen, LM Soveri… - The Lancet Regional …, 2021 - thelancet.com
Background Resection of colorectal cancer (CRC) metastases provides good survival but is
probably underused in real-world practice. Methods A prospective Finnish nationwide study …
probably underused in real-world practice. Methods A prospective Finnish nationwide study …
The liver–immunity nexus and cancer immunotherapy
JC Lee, MD Green, LA Huppert, C Chow… - Clinical Cancer …, 2022 - AACR
The impact of liver metastases on immune checkpoint-inhibitor effectiveness in patients with
solid-tumor malignancies has been the focus of several recent clinical and translational …
solid-tumor malignancies has been the focus of several recent clinical and translational …
Survival outcomes after portal vein embolization and liver resection compared with liver transplant for patients with extensive colorectal cancer liver metastases
S Dueland, S Yaqub, T Syversveen, U Carling… - JAMA …, 2021 - jamanetwork.com
Importance Portal vein embolization (PVE) has been implemented in patients with extensive
colorectal liver metastases to increase the number of patients able to undergo liver …
colorectal liver metastases to increase the number of patients able to undergo liver …
Biomarkers of response and resistance to immunotherapy in microsatellite stable colorectal cancer: toward a new personalized medicine
N Huyghe, E Benidovskaya, P Stevens… - Cancers, 2022 - mdpi.com
Simple Summary Immune Checkpoint Inhibitors (ICIs) have demonstrated clinical efficacy in
Microsatellite Instability High Colorectal Cancer (MSI-H CRC). However, in Microsatellite …
Microsatellite Instability High Colorectal Cancer (MSI-H CRC). However, in Microsatellite …
Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition
C Hu, M Ye, J Bai, P Liu, F Lu, J Chen, P Yu… - Cancer Cell …, 2023 - Springer
Background It has been manifested in several studies that age-related metabolic
reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC) …
reprogramming is associated with tumor progression, in particular, colorectal cancer (CRC) …
Efficacy of near-infrared fluorescence-guided hepatectomy for the detection of colorectal liver metastases: a randomized controlled trial
BACKGROUND: The application of indocyanine green fluorescence–guided hepatectomy
for liver metastases from colorectal cancer is in the preliminary stage of clinical practice; …
for liver metastases from colorectal cancer is in the preliminary stage of clinical practice; …
Colorectal cancer: current updates and future perspectives
Colorectal cancer is a frequent neoplasm in western countries, mainly due to dietary and
behavioral factors. Its incidence is growing in develo** countries for the westernization of …
behavioral factors. Its incidence is growing in develo** countries for the westernization of …
MTA1, a novel ATP synthase complex modulator, enhances colon cancer liver metastasis by driving mitochondrial metabolism reprogramming
T Wang, F Sun, C Li, P Nan, Y Song, X Wan… - Advanced …, 2023 - Wiley Online Library
Liver metastasis is the most fatal event of colon cancer patients. Warburg effect has been
long challenged by the fact of upregulated oxidative phosphorylation (OXPHOS), while its …
long challenged by the fact of upregulated oxidative phosphorylation (OXPHOS), while its …