Objectives: An overview of biochemical markers of bone metabolism is presented along with
indications for their clinical utilization. Design and Methods: The structure, cyclical …

I. Introduction THERE is increasing awareness among scientists, clinicians, policy makers,
and the general public of the costs and health care problems associated with osteoporosis …

Osteoporosis is a disease characterized by low bone mass and by architectural deterioration
of bone tissue, two factors related to abnormalities of bone turnover. Histomorphometric …

Background and objectives Use of bone mineral density (BMD) by dual-energy x-ray
absorptiometry (DXA) is controversial for diagnosing bone loss in CKD patients on dialysis …

The noninvasive assessment of bone turnover has received increasing attention over the
past few years because of the need for sensitive markers in the clinical investigation of …

The noninvasive assessment of bone turnover has markedly improved in the past few years
with the development of sensitive and specific markers of bone formation and bone …

The various conventional and newly discovered biochemical markers of bone formation,
such as serum alkaline phosphatase and bone GLA-protein (osteocalcin), and of bone …

To study the mechanism of bone loss in physical unloading, we examined indices of bone
formation and bone resorption in the serum and urine of eight healthy men during a 7 day …

Aim: To investigate the potential of a thermosensitive intranasal formulation of raloxifene
hydrochloride (RH) for systemic delivery with the possibility of enhanced bioavailability and …

The non-invasive assessment of bone turnover has received increasing attention over the
past few years because of the need for sensitive markers in the clinical investigation of …