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Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases
S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
The emerging antioxidant paradigm of mesenchymal stem cell therapy
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …
the treatment of diverse diseases, with many promising outcomes achieved in animal …
Targeting angiogenesis and lymphangiogenesis in kidney disease
K Tanabe, J Wada, Y Sato - Nature Reviews Nephrology, 2020 - nature.com
The kidney is permeated by a highly complex vascular system with glomerular and
peritubular capillary networks that are essential for maintaining the normal functions of …
peritubular capillary networks that are essential for maintaining the normal functions of …
Research progress of extracellular vesicles and exosomes derived from mesenchymal stem cells in the treatment of oxidative stress-related diseases
W Zhang, T Wang, Y Xue, B Zhan, Z Lai… - Frontiers in …, 2023 - frontiersin.org
There is growing evidence that mesenchymal stem cell-derived extracellular vesicles and
exosomes can significantly improve the curative effect of oxidative stress-related diseases …
exosomes can significantly improve the curative effect of oxidative stress-related diseases …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury
L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
Potential and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for acute/chronic kidney disease
CW Yun, SH Lee - International journal of molecular sciences, 2019 - mdpi.com
Kidney disease can be either acute kidney injury (AKI) or chronic kidney disease (CKD) and
it can lead to the development of functional organ failure. Mesenchymal stem cells (MSCs) …
it can lead to the development of functional organ failure. Mesenchymal stem cells (MSCs) …
Mesenchymal stem cell-derived extracellular vesicles in tissue regeneration
B Zhang, X Tian, J Hao, G Xu… - Cell transplantation, 2020 - journals.sagepub.com
Mesenchymal stem cells (MSCs) are multipotent stem cells that have attracted increasing
interest in the field of regenerative medicine. Previously, the differentiation ability of MSCs …
interest in the field of regenerative medicine. Previously, the differentiation ability of MSCs …
[HTML][HTML] Understanding molecular characteristics of extracellular vesicles derived from different types of mesenchymal stem cells for therapeutic translation
Mesenchymal stem cells (MSCs) have been studied for decades as candidates for cellular
therapy, and their secretome, including secreted extracellular vesicles (EVs), has been …
therapy, and their secretome, including secreted extracellular vesicles (EVs), has been …
Conditioned medium of mesenchymal stromal cells: a new class of therapeutics
NV Bogatcheva, ME Coleman - Biochemistry (Moscow), 2019 - Springer
Mesenchymal stromal cell (MSCs) represent a class of biologics with the prospects for
employment as immunomodulatory, tissue-protective, and regenerative therapeutics. In …
employment as immunomodulatory, tissue-protective, and regenerative therapeutics. In …