“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates
SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …
significant roles in a variety of vital biological processes. Access to unique and …
Advances in the biology and chemistry of sialic acids
Sialic acids are a subset of nonulosonic acids, which are nine-carbon α-keto aldonic acids.
Natural existing sialic acid-containing structures are presented in different sialic acid forms …
Natural existing sialic acid-containing structures are presented in different sialic acid forms …
A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N-Glycans
A systematic, efficient means of producing diverse libraries of asymmetrically branched N-
glycans is needed to investigate the specificities and biology of glycan-binding proteins. To …
glycans is needed to investigate the specificities and biology of glycan-binding proteins. To …
Toward automated oligosaccharide synthesis
CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …
of development in carbohydrate research is, however, relatively slow due to the problems …
Stereoselective Synthesis of Sialyl Lewisa Antigen and the Effective Anticancer Activity of Its Bacteriophage Qβ Conjugate as an Anticancer Vaccine
Z Rashidijahanabad, S Ramadan… - Angewandte Chemie …, 2023 - Wiley Online Library
Sialyl Lewisa (sLea), also known as cancer antigen 19‐9 (CA19‐9), is a tumor‐associated
carbohydrate antigen. The overexpression of sLea on the surface of a variety of cancer cells …
carbohydrate antigen. The overexpression of sLea on the surface of a variety of cancer cells …
Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
L Liu, AR Prudden, CJ Capicciotti, GP Bosman… - Nature …, 2019 - nature.com
Contemporary chemoenzymatic approaches can provide highly complex multi-antennary N-
linked glycans. These procedures are, however, very demanding and typically involve as …
linked glycans. These procedures are, however, very demanding and typically involve as …
Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions
LX Wang, MN Amin - Chemistry & biology, 2014 - cell.com
Glycoproteins are an important class of biomolecules involved in a number of biological
recognition processes. However, natural and recombinant glycoproteins are usually …
recognition processes. However, natural and recombinant glycoproteins are usually …
Gold(I)‐Catalyzed Glycosylation with Glycosyl ortho‐Alkynylbenzoates as Donors: General Scope and Application in the Synthesis of a Cyclic Triterpene Saponin
Glycosyl ortho‐alkynylbenzoates have emerged as a new generation of donors for
glycosidation under the catalysis of gold (I) complexes such as Ph3PAuOTf and …
glycosidation under the catalysis of gold (I) complexes such as Ph3PAuOTf and …
Glycosylation with glycosyl N-phenyltrifluoroacetimidates (PTFAI) and a perspective of the future development of new glycosylation methods
B Yu, J Sun - Chemical communications, 2010 - pubs.rsc.org
The glycosyl N-phenyltrifluoroacetimidates (PTFAI) have within the last ten years been
applied in the synthesis of a wide variety of the oligosaccharides and glycoconjugates …
applied in the synthesis of a wide variety of the oligosaccharides and glycoconjugates …
Establishment of guidelines for the control of glycosylation reactions and intermediates by quantitative assessment of reactivity
CW Chang, CH Wu, MH Lin, PH Liao… - Angewandte …, 2019 - Wiley Online Library
Stereocontrolled chemical glycosylation remains a major challenge despite vast efforts
reported over many decades and so far still mainly relies on trial and error. Now it is shown …
reported over many decades and so far still mainly relies on trial and error. Now it is shown …