The role of transcriptional regulators in metal ion homeostasis of Mycobacterium tuberculosis

S Wang, R Fang, H Wang, X Li, J **ng, Z Li… - Frontiers in Cellular …, 2024 - frontiersin.org
Metal ions are essential trace elements for all living organisms and play critical catalytic,
structural, and allosteric roles in many enzymes and transcription factors. Mycobacterium …

Copper sensing transcription factor ArsR2 regulates VjbR to sustain virulence in Brucella abortus

F Zhi, K Liu, H Geng, M Su, J Xu, L Fu… - Emerging Microbes & …, 2024 - Taylor & Francis
Brucellosis, caused by the intracellular pathogen Brucella, is a major zoonotic infection that
promotes reproductive disease in domestic animals and chronic debilitating conditions in …

MLDSR, the transcriptional regulator of the major lipid droplets protein MLDS, is controlled by long‐chain fatty acids and contributes to the lipid‐accumulating …

MA Hernández, AE Ledesma, G Moncalián… - The FEBS …, 2024 - Wiley Online Library
Microorganism lipid droplet small regulator (MLDSR) is a transcriptional regulator of the
major lipid droplet (LD)‐associated protein MLDS in Rhodococcus jostii RHA1 and …

HigA2 (Rv2021c) Is a Transcriptional Regulator with Multiple Regulatory Targets in Mycobacterium tuberculosis

M Xu, M Liu, T Liu, X Pan, Q Ren, T Han, L Gou - Microorganisms, 2024 - mdpi.com
Toxin-antitoxin (TA) systems are the major mechanism for persister formation in
Mycobacterium tuberculosis (Mtb). Previous studies found that HigBA2 (Rv2022c-Rv2021c) …

Insights into the evolutionary history of the virulent factor HBHA of Mycobacterium tuberculosis

MP Lanfranconi, A Arabolaza, H Gramajo… - Archives of …, 2021 - Springer
In Mycobacterium tuberculosis, heparin-binding hemagglutinin (HBHAMT) has a relevant
role in infection. It is also present in non-virulent mycobacteria and ancient actinobacteria …

Coordinate regulation of virulence and metabolic genes by the transcription factor HbhR in Mycobacterium marinum

D Raze, J Segers, C Mille, S Slupek… - Molecular …, 2020 - Wiley Online Library
The heparin‐binding hemagglutinin (HBHA) is a multifunctional protein involved in
adherence of Mycobacterium tuberculosis to non‐phagocytic cells and in the formation of …

MSMEG_0918 is not Essential for the Growth of Mycobacterium smegmatis

E Bedru, A Bhagwat, T Parish - Micropublication Biology, 2024 - pmc.ncbi.nlm.nih.gov
Copper homeostasis plays a crucial role in mycobacteria. In Mycobacterium tuberculosis,
Rv0474 is a copper-responsive regulator with a copper-binding motif but its homolog in …