Depression is a complicated neuropsychiatric condition with an incompletely understood
etiology, making the discovery of effective therapies challenging. Animal models have been …

There are previous epidemiological studies reporting associations between antibiotic use
and psychiatric symptoms. Antibiotic-induced gut dysbiosis and alteration of microbiota-gut …

Aging-associated cognitive dysfunction has a great influence on the lifespan and healthspan
of the elderly. Theaflavins (TFs), a mixture of ingredients formed from enzymatic oxidation of …

Remyelination failure in diseases like multiple sclerosis (MS) was thought to involve
suppressed maturation of oligodendrocyte precursors; however, oligodendrocytes are …

Abstract Ethnopharmacological relevance Kai-**n-San (KXS) is a classic famous
prescription that has been utilized for centuries to address dementia. New investigations …

Objectives: The aim of this study was to investigate the ameliorative effect of platycodin D
(PD) on cognitive dysfunction in type 2 diabetes mellitus (T2DM) and its potential molecular …

Neuropsychiatric disorders have been one of the worldwide health problems contributing to
profound social and economic consequences. It is reported that consumption of an …

Aims Neuroinflammation plays a pivotal role in amyloid β (Aβ) plaques formation which is
among the hallmarks of Alzheimer's disease (AD). The present study investigated the …

The decreased ability of mature oligodendrocytes to produce myelin negatively affects
remyelination in demyelinating diseases and aging, but the underlying mechanisms are …

Alzheimer's disease (AD) stands as the predominant age-related neurodegenerative
disorder, for which efficacious treatment remains elusive. An auspicious avenue for this …