Neuroimmune mechanisms as novel treatment targets for substance use disorders and associated comorbidities

MD Namba, JM Leyrer-Jackson, EK Nagy… - Frontiers in …, 2021 - frontiersin.org
Recent studies examining the neurobiology of substance abuse have revealed a significant
role of neuroimmune signaling as a mechanism through which drugs of abuse induce …

The biological impact of menthol on tobacco dependence

RJ Wickham - Nicotine and Tobacco Research, 2020 - academic.oup.com
In the 1920s, tobacco companies created a marketing campaign for what would one day be
their most profitable series of products: mentholated tobacco cigarettes. Menthol provides …

Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central …

D Kennedy, E Okello, P Chazot, MJ Howes… - Nutrients, 2018 - mdpi.com
Background: Extracts of several members of the monoterpene-rich Lamiaceae sub-family
Nepetoideae, including those from the Salvia (sage), Melissa (Lemon balm) and …

Cellular and molecular targets of menthol actions

M Oz, EG El Nebrisi, KHS Yang, FC Howarth… - Frontiers in …, 2017 - frontiersin.org
Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals
found in plant-derived essential oils. Menthol is widely used in pharmaceuticals …

The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances

Z Li, H Zhang, Y Wang, Y Li, Q Li… - Frontiers in Molecular …, 2022 - frontiersin.org
Menthol is an important flavoring additive that triggers a cooling sensation. Under
physiological condition, low to moderate concentrations of menthol activate transient …

[HTML][HTML] Menthol inhibits oxidative stress and inflammation in acetic acid-induced colitis in rat colonic mucosa

SMA Bastaki, E Adeghate, N Amir… - American journal of …, 2018 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease are
characterized by chronic inflammation of the gastrointestinal system. There is no permanent …

Allosteric modulation of nicotinic acetylcholine receptors

A Chatzidaki, NS Millar - Biochemical pharmacology, 2015 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) are receptors for the neurotransmitter
acetylcholine and are members of the 'Cys-loop'family of pentameric ligand-gated ion …

Effects of menthol on nicotine pharmacokinetic, pharmacology and dependence in mice

SD Alsharari, JR King, JC Nordman, PP Muldoon… - PloS one, 2015 - journals.plos.org
Although menthol, a common flavoring additive to cigarettes, has been found to impact the
addictive properties of nicotine cigarettes in smokers little is known about its …

Effects of monoterpenes on ion channels of excitable cells

M Oz, Y Lozon, A Sultan, KHS Yang… - Pharmacology & …, 2015 - Elsevier
Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of
plant-derived 'essential oils'. Monoterpenes such as menthol, carvacrol, and eugenol have …

Metabolic determinants of Alzheimer's disease: A focus on thermoregulation

M Tournissac, M Leclerc, J Valentin-Escalera… - Ageing Research …, 2021 - Elsevier
Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …