Glia development and function in the nematode Caenorhabditis elegans

A Singhvi, S Shaham, G Rapti - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
The nematode Caenorhabditis elegans is a powerful experimental setting for uncovering
fundamental tenets of nervous system organization and function. Its nearly invariant and …

Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans

CG Martin, JS Bent, T Hill, I Topalidou, A Singhvi - Developmental Cell, 2024 - cell.com
For an organ to maintain correct architecture and function, its diverse cellular components
must coordinate their size and shape. Although cell-intrinsic mechanisms driving homotypic …

Direct glia-to-neuron transdifferentiation gives rise to a pair of male-specific neurons that ensure nimble male mating

L Molina-García, C Lloret-Fernandez, SJ Cook, B Kim… - Elife, 2020 - elifesciences.org
Sexually dimorphic behaviours require underlying differences in the nervous system
between males and females. The extent to which nervous systems are sexually dimorphic …

Cell-type-specific promoters for C. elegans glia

W Fung, L Wexler, MG Heiman - Journal of neurogenetics, 2020 - Taylor & Francis
Glia shape the development and function of the C. elegans nervous system, especially its
sense organs and central neuropil (nerve ring). Cell-type-specific promoters allow …