Trace amines and their receptors

RR Gainetdinov, MC Hoener, MD Berry… - Pharmacological …, 2018 - Elsevier
Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

[HTML][HTML] Thyroid hormone regulation of metabolism

R Mullur, YY Liu, GA Brent - Physiological reviews, 2014 - journals.physiology.org
Thyroid hormone (TH) is required for normal development as well as regulating metabolism
in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially …

Chemistry and biology in the biosynthesis and action of thyroid hormones

S Mondal, K Raja, U Schweizer… - Angewandte Chemie …, 2016 - Wiley Online Library
Thyroid hormones (THs) are secreted by the thyroid gland. They control lipid, carbohydrate,
and protein metabolism, heart rate, neural development, as well as cardiovascular, renal …

[PDF][PDF] THEMATIC REVIEW Deiodinases: the balance of thyroid hormone Type 1 iodothyronine deiodinase in human physiology and disease

AL Maia, IM Goemann, ELS Meyer… - Journal of …, 2011 - academia.edu
Thyroid hormone is essential for the normal function of virtually all tissues. The
iodothyronine deiodinases catalyze the removal of an iodine residue from the pro-hormone …

Metabolic effects of thyroid hormone derivatives

M Moreno, P de Lange, A Lombardi, E Silvestri… - Thyroid, 2008 - liebertpub.com
The processes and pathways mediating the intermediary metabolism of carbohydrates,
lipids, and proteins are all affected by thyroid hormones (THs) in almost all tissues. Particular …

TSH and thyrotropic agonists: key actors in thyroid homeostasis

JW Dietrich, G Landgrafe… - Journal of thyroid …, 2012 - Wiley Online Library
This paper provides the reader with an overview of our current knowledge of hypothalamic‐
pituitary‐thyroid feedback from a cybernetic standpoint. Over the past decades we have …

Metabolic downregulation: a key to successful neuroprotection?

M Yenari, K Kitagawa, P Lyden, M Perez-Pinzon - Stroke, 2008 - Am Heart Assoc
Background and Purpose—The search for effective neuroprotectants remains frustrating,
particularly with regard to specific pharmaceuticals. However, laboratory studies have …

Thyroid hormones in the brain and their impact in recovery mechanisms after stroke

D Talhada, CRA Santos, I Gonçalves… - Frontiers in …, 2019 - frontiersin.org
Thyroid hormones are of fundamental importance for brain development and essential
factors to warrant brain functions throughout life. Their actions are mediated by binding to …

Thyronamines—past, present, and future

S Piehl, CS Hoefig, TS Scanlan, J Köhrle - Endocrine reviews, 2011 - academic.oup.com
After their initial discovery in the early 1950's, thyronamines (TAM), a class of endogenous
signalling compounds exhibiting structural similarity to the thyroid hormone L-thyroxine, are …

The colorful diversity of thyroid hormone metabolites

J Köhrle - European Thyroid Journal, 2019 - etj.bioscientifica.com
Since the discovery of L-thyroxine, the main secretory product of the thyroid gland, and its
major metabolite T3, which exerts the majority of thyroid hormone action via ligand …