The high-throughput-next generation sequencing (HT-NGS) technologies are currently the
hottest topic in the field of human and animals genomics researches, which can produce …

Phenotypic plasticity is the development of different phenotypes from a single genotype,
depending on the environment. Such plasticity is a pervasive feature of life, is observed for …

We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

High-throughput sequencing technologies have strongly impacted microbiology, providing a
rapid and cost-effective way of generating draft genomes and exploring microbial diversity …

The next-generation sequencing (NGS) revolution has drastically reduced time and cost
requirements for sequencing of large genomes, and also qualitatively changed the problem …

As our ability to generate sequencing data continues to increase, data analysis is replacing
data generation as the rate-limiting step in genomics studies. Here we provide a guide to …

As one of the key technologies in biomedical research, DNA sequencing has not only
improved its productivity with an exponential growth rate but also been applied to new areas …

There is a growing gap between the generation of massively parallel sequencing output and
the ability to process and analyze the resulting data. New users are left to navigate a …

Recent efforts of researchers to elucidate the molecular mechanisms of biological systems
have been revolutionized greatly with the use of high throughput and cost-effective …

Abstract Background The FVB/NJ mouse strain has its origins in a colony of outbred Swiss
mice established in 1935 at the National Institutes of Health. Mice derived from this source …