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Next-generation physiology approaches to study microbiome function at single cell level
The function of cells in their native habitat often cannot be reliably predicted from genomic
data or from physiology studies of isolates. Traditional experimental approaches to study the …
data or from physiology studies of isolates. Traditional experimental approaches to study the …
[HTML][HTML] Optical tweezers: Phototoxicity and thermal stress in cells and biomolecules
A Blázquez-Castro - Micromachines, 2019 - mdpi.com
For several decades optical tweezers have proven to be an invaluable tool in the study and
analysis of myriad biological responses and applications. However, as with every tool, they …
analysis of myriad biological responses and applications. However, as with every tool, they …
[HTML][HTML] Dissecting horizontal and vertical gene transfer of antibiotic resistance plasmid in bacterial community using microfluidics
B Li, Y Qiu, Y Song, H Lin, H Yin - Environment International, 2019 - Elsevier
The spread of antibiotic resistance genes (ARGs) has become an emerging threat to the
global health. Although horizontal gene transfer (HGT) is regarded as one of the major …
global health. Although horizontal gene transfer (HGT) is regarded as one of the major …
Raman spectroscopy combined with machine learning for rapid detection of food-borne pathogens at the single-cell level
S Yan, S Wang, J Qiu, M Li, D Li, D Xu, D Li, Q Liu - Talanta, 2021 - Elsevier
Rapid detection of food-borne pathogens in early food contamination is a permanent topic to
ensure food safety and prevent public health problems. Raman spectroscopy, a label-free …
ensure food safety and prevent public health problems. Raman spectroscopy, a label-free …
A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons
Stem cells with the capability to self-renew and differentiate into multiple cell derivatives
provide platforms for drug screening and promising treatment options for a wide variety of …
provide platforms for drug screening and promising treatment options for a wide variety of …
Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution
Phenotypic profiling of natural, engineered or synthetic cells has increasingly become a
bottleneck in the mining and engineering of cell factories. Single-cell phenoty** …
bottleneck in the mining and engineering of cell factories. Single-cell phenoty** …
High-speed diagnosis of bacterial pathogens at the single cell level by Raman microspectroscopy with machine learning filters and denoising autoencoders
J Xu, X Yi, G **, D Peng, G Fan, X Xu… - ACS Chemical …, 2022 - ACS Publications
Accurate and rapid identification of infectious bacteria is important in medicine. Raman
microspectroscopy holds great promise in performing label-free identification at the single …
microspectroscopy holds great promise in performing label-free identification at the single …
Optofluidic Raman-activated cell sorting for targeted genome retrieval or cultivation of microbial cells with specific functions
Stable isotope labeling of microbial taxa of interest and their sorting provide an efficient and
direct way to answer the question “who does what?” in complex microbial communities …
direct way to answer the question “who does what?” in complex microbial communities …
High-speed compressed-sensing fluorescence lifetime imaging microscopy of live cells
We present high-resolution, high-speed fluorescence lifetime imaging microscopy (FLIM) of
live cells based on a compressed sensing scheme. By leveraging the compressibility of …
live cells based on a compressed sensing scheme. By leveraging the compressibility of …
Self-assembled plasmonic nanoarrays for enhanced bacterial identification and discrimination
The rapid and accurate bacterial testing is a critical step for the management of infectious
diseases, but challenges remain largely due to a lack of advanced sensing tools. Here we …
diseases, but challenges remain largely due to a lack of advanced sensing tools. Here we …