Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons

M Thouaye, I Yalcin - Pharmacology & therapeutics, 2023 - Elsevier
Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Pathology of pain and its implications for therapeutic interventions

B Cao, Q Xu, Y Shi, R Zhao, H Li, J Zheng… - … and Targeted Therapy, 2024 - nature.com
Pain is estimated to affect more than 20% of the global population, imposing incalculable
health and economic burdens. Effective pain management is crucial for individuals suffering …

Nociceptive, neuropathic, or nociplastic low back pain? The low back pain phenoty** (BACPAP) consortium's international and multidisciplinary consensus …

J Nijs, E Kosek, A Chiarotto, C Cook… - The Lancet …, 2024 - thelancet.com
The potential to classify low back pain as being characterised by dominant nociceptive,
neuropathic, or nociplastic mechanisms is a clinically relevant issue. Preliminary evidence …

[HTML][HTML] Brain mechanisms of exercise-induced hypoalgesia: to find a way out from “fear-avoidance belief”

K Kami, F Tajima, E Senba - International Journal of Molecular Sciences, 2022 - mdpi.com
It is well known that exercise produces analgesic effects (exercise-induced hypoalgesia
(EIH)) in animal models and chronic pain patients, but the brain mechanisms underlying …

Role of exercise on inflammation cytokines of neuropathic pain in animal models

YN Zheng, YL Zheng, XQ Wang, PJ Chen - Molecular Neurobiology, 2024 - Springer
Neuropathic pain (NP) resulting from a lesion or disease of the somatosensory system can
lead to loss of function and reduced life quality. Neuroinflammation plays a vital role in the …

Physical activity should be the primary intervention for individuals living with chronic pain A position paper from the European Pain Federation (EFIC)'On the Move' …

HB Vaegter, M Kinnunen, J Verbrugghe… - … Journal of Pain, 2024 - Wiley Online Library
Background There is clear evidence demonstrating the benefits of physical activity (PA) on
pain and overall health, however, PA is challenging for many individuals living with chronic …

Precision management of post‐COVID pain: An evidence and clinical‐based approach

C Fernández‐de‐las‐Peñas, J Nijs… - … Journal of Pain, 2023 - Wiley Online Library
Background Pain after a SARS‐CoV‐2 acute infection (post‐COVID pain) is becoming a
new healthcare emergency but remains underestimated and most likely undertreated due to …

[HTML][HTML] Analgesic effect of dance movement therapy: An fNIRS study

CC Wu, J Yang, XQ Wang - NeuroImage, 2024 - Elsevier
Objective This study aims to explores the physiological and psychological mechanisms of
exercise-induced hypoalgesia (EIH) by combining the behavioral results with neuroimaging …

The effect and mechanism of exercise for post-stroke pain

Y Ma, J Luo, XQ Wang - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
One of the common negative effects of a stroke that seriously lowers patients' quality of life is
post-stroke pain (PSP). Thus, exercise in PSP management has become a hot research …

The voltage-gated calcium channel α2δ subunit in neuropathic pain

SJ Guo, YQ Shi, YN Zheng, H Liu, YL Zheng - Molecular Neurobiology, 2024 - Springer
Neuropathic pain (NP) is a chronic pain caused by injury or disease of the somatosensory
nervous system, or it can be directly caused by disease. It often presents with clinical …