The molecular mechanisms underlying anti‐inflammatory effects of galangin in different diseases
When used as an alternative source of drugs to treat inflammation‐associated diseases,
phytochemicals with anti‐inflammatory properties provide beneficial impacts. Galangin is …
phytochemicals with anti‐inflammatory properties provide beneficial impacts. Galangin is …
Nrf2/HO-1 as a therapeutic target in renal fibrosis
Chronic kidney disease (CKD) is one of the most prevalent chronic diseases and affects
between 10 and 14% of the world's population. The World Health Organization estimates …
between 10 and 14% of the world's population. The World Health Organization estimates …
Dihydromyricetin attenuates cisplatin-induced acute kidney injury by reducing oxidative stress, inflammation and ferroptosis
Z Xu, M Zhang, W Wang, S Zhou, M Yu, X Qiu… - Toxicology and Applied …, 2023 - Elsevier
Background Cisplatin is effective against various types of cancers. However, its clinical
application is limited owing to its adverse effects, especially acute kidney injury (AKI) …
application is limited owing to its adverse effects, especially acute kidney injury (AKI) …
Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury in rats by modulating SIRT1 and Nrf2/HO-1 signaling
Chlorpyrifos (CPF) is a widely used broad-spectrum pesticide with multi-organ toxic effects.
Oxidative stress was found to play a role in the deleterious effects of CPF, including …
Oxidative stress was found to play a role in the deleterious effects of CPF, including …
7-hydroxycoumarin-β-D-glucuronide protects against cisplatin-induced acute kidney injury via inhibiting p38 MAPK-mediated apoptosis in mice
H Wu, X Shi, Y Zang, X Zhao, X Liu, W Wang, W Shi… - Life Sciences, 2023 - Elsevier
Aims Cisplatin is a widely-used drug in the clinical treatment of tumors, but kidney
nephrotoxicity is one of the reasons that limits its widespread use. We previously found that …
nephrotoxicity is one of the reasons that limits its widespread use. We previously found that …
Azithromycin mitigates cisplatin-induced lung oxidative stress, inflammation and necroptosis by upregulating SIRT1, PPARγ, and Nrf2/HO-1 signaling
Acute lung injury (ALI) is one of the adverse effects of the antineoplastic agent cisplatin
(CIS). Oxidative stress, inflammation, and necroptosis are linked to the emergence of lung …
(CIS). Oxidative stress, inflammation, and necroptosis are linked to the emergence of lung …
Flavonoids of Haloxylon salicornicum (Rimth) prevent cisplatin-induced acute kidney injury by modulating oxidative stress, inflammation, Nrf2, and SIRT1
Cisplatin (CIS) is an effective chemotherapeutic drug used for the treatment of many types of
cancers, but its use is associated with adverse effects. Nephrotoxicity is a serious side effect …
cancers, but its use is associated with adverse effects. Nephrotoxicity is a serious side effect …
Taxifolin prevents cisplatin nephrotoxicity by modulating Nrf2/HO-1 pathway and mitigating oxidative stress and inflammation in mice
Cisplatin (CIS) is an effective chemotherapeutic agent used in the treatment of several
malignancies. The clinical use of CIS is associated with adverse effects, including acute …
malignancies. The clinical use of CIS is associated with adverse effects, including acute …
A comparative metabolomics analysis of phytochemcials and antioxidant activity between broccoli floret and by-products (leaves and stalks)
Y Zhao, Y Zhang, H Yang, Z Xu, Z Li, Z Zhang… - Food Chemistry, 2024 - Elsevier
Leaves and stalks, which account for about 45% and 25% of broccoli biomass, respectively,
are usually discarded during broccoli production, leading to the waste of green resources. In …
are usually discarded during broccoli production, leading to the waste of green resources. In …
A flavonoid-rich fraction of Euphorbia peplus attenuates hyperglycemia, insulin resistance, and oxidative stress in a type 2 diabetes rat model
Background: Type 2 diabetes (T2D) is a metabolic disorder characterized by insulin
resistance (IR) and hyperglycemia. Plants are valuable sources of therapeutic agents for the …
resistance (IR) and hyperglycemia. Plants are valuable sources of therapeutic agents for the …