The DNA motif discovery is a primary step in many systems for studying gene function. Motif
discovery plays a vital role in identification of Transcription Factor Binding Sites (TFBSs) that …

Recent transcriptome analysis indicates that> 90% of human genes undergo alternative
splicing, underscoring the contribution of differential RNA processing to diverse proteomes …

Abstract Background The Codon Adaptation Index (CAI) is a measure of the synonymous
codon usage bias for a DNA or RNA sequence. It quantifies the similarity between the …

Circular RNAs (circRNAs), which play vital roles in many regulatory pathways, are
widespread in many species. Although many circRNAs have been discovered in plants and …

Small proteins (10–200 amino acids [aa] in length) encoded by short open reading frames
(sORF) play important regulatory roles in various biological processes, including tumor …

Codons that code for the same amino acid are often used with unequal frequencies. This
phenomenon is termed codon bias. Here, we report a computational analysis of codon bias …

Background Low-complexity data analysis is the area that addresses the search and
quantification of regions in sequences of elements that contain low-complexity or repetitive …

The conjugative IncHI1 plasmid pSfR27 from Shigella flexneri 2a strain 2457T encodes the
Sfh protein, a paralogue of the global transcriptional repressor H‐NS. Sfh allows pSfR27 to …

Pyrrolysyl-tRNA synthetase and its cognate suppressor tRNAPyl mediate pyrrolysine (Pyl)
insertion at in frame UAG codons. The presence of an RNA hairpin structure named Pyl …

Background Antimicrobial peptides are a promising alternative to conventional antibiotics.
Plants are an important source of such peptides; their pharmacological properties are known …