Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

H Yoshiji, S Nagoshi, T Akahane, Y Asaoka… - Journal of …, 2021‏ - Springer
The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Overview of complications in cirrhosis

M Premkumar, AC Anand - Journal of Clinical and Experimental …, 2022‏ - Elsevier
Background Cirrhosis is the outcome of chronic liver disease of any etiology due to
progressive liver injury and fibrosis. Consequently, cirrhosis leads to portal hypertension …

Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis

H Nishikawa, H Enomoto, A Ishii, Y Iwata… - Journal of cachexia …, 2017‏ - Wiley Online Library
Background We aimed to elucidate the relationship between serum myostatin levels and
other markers including skeletal muscle mass and to investigate the influence of serum …

[HTML][HTML] Role of gut dysbiosis in liver diseases: what have we learned so far?

H Fukui - Diseases, 2019‏ - mdpi.com
Accumulating evidence supports that gut dysbiosis may relate to various liver diseases.
Alcoholics with high intestinal permeability had a decrease in the abundance of …

Screening and identifying hepatobiliary diseases through deep learning using ocular images: a prospective, multicentre study

W **ao, X Huang, JH Wang, DR Lin, Y Zhu… - The Lancet Digital …, 2021‏ - thelancet.com
Background Ocular changes are traditionally associated with only a few hepatobiliary
diseases. These changes are non-specific and have a low detection rate, limiting their …

Serum exosomal microRNA, miR-10b-5p, as a potential diagnostic biomarker for early-stage hepatocellular carcinoma

HJ Cho, JW Eun, GO Baek, CW Seo, HR Ahn… - Journal of Clinical …, 2020‏ - mdpi.com
Exosomal microRNAs (exo-miRs) have been promising cancer biomarkers. MiRs in
hepatocellular carcinoma (HCC) cell-derived exosomes (HEX) were analyzed to identify …

Reduced handgrip strength predicts poorer survival in chronic liver diseases: a large multicenter study in Japan

H Nishikawa, M Shiraki, A Hiramatsu… - Hepatology …, 2021‏ - Wiley Online Library
Aim Sarcopenia has a high prevalence and can be an adverse predictor in patients with
chronic liver diseases (CLDs). We sought to assess the prevalence of sarcopenia and its …

Sarcopenia and frailty in liver cirrhosis

H Nishikawa, S Fukunishi, A Asai, S Nishiguchi… - Life, 2021‏ - mdpi.com
Skeletal muscle is the largest organ in the body, and skeletal muscle atrophy results from a
shift in the balance of protein synthesis and degradation toward protein breakdown. Primary …

When albumin meets liposomes: A feasible drug carrier for biomedical applications

K Taguchi, Y Okamoto, K Matsumoto, M Otagiri… - Pharmaceuticals, 2021‏ - mdpi.com
Albumin, the most abundant protein in plasma, possesses some inherent beneficial
structural and physiological characteristics that make it suitable for use as a drug delivery …

Reduced handgrip strength is predictive of poor survival among patients with liver cirrhosis: a sex‐stratified analysis

T Hanai, M Shiraki, K Imai, A Suetsugu… - Hepatology …, 2019‏ - Wiley Online Library
Aim Handgrip strength (HGS) is a marker of sarcopenia and has been used to stratify an
individual's risk of death. We aimed to assess the prognostic significance of HGS in patients …