Maternal immune activation and abnormal brain development across CNS disorders

I Knuesel, L Chicha, M Britschgi, SA Schobel… - Nature Reviews …, 2014 - nature.com
Epidemiological studies have shown a clear association between maternal infection and
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …

Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia

FL Haddad, SV Patel, S Schmid - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Developmental neuroinflammation and schizophrenia

U Meyer - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
There is increasing interest in and evidence for altered immune factors in the etiology and
pathophysiology of schizophrenia. Stimulated by various epidemiological findings reporting …

DTIPrep: quality control of diffusion-weighted images

I Oguz, M Farzinfar, J Matsui, F Budin, Z Liu… - Frontiers in …, 2014 - frontiersin.org
In the last decade, diffusion MRI (dMRI) studies of the human and animal brain have been
used to investigate a multitude of pathologies and drug-related effects in neuroscience …

Evidence for a dysregulated immune system in the etiology of psychiatric disorders

SM Gibney, HA Drexhage - Journal of Neuroimmune Pharmacology, 2013 - Springer
There is extensive bi-directional communication between the brain and the immune system
in both health and disease. In recent years, the role of an altered immune system in the …

Genome-wide DNA methylation changes in a mouse model of infection-mediated neurodevelopmental disorders

J Richetto, R Massart, U Weber-Stadlbauer, M Szyf… - Biological …, 2017 - Elsevier
Background Prenatal exposure to infectious or inflammatory insults increases the risk of
neurodevelopmental disorders. Using a well-established mouse model of prenatal viral-like …

Neuroinflammation in autism: plausible role of maternal inflammation, dietary omega 3, and microbiota

C Madore, Q Leyrolle, C Lacabanne… - Neural …, 2016 - Wiley Online Library
Several genetic causes of autism spectrum disorder (ASD) have been identified. However,
more recent work has highlighted that certain environmental exposures early in life may also …

Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice

TV Lipina, C Zai, D Hlousek, JC Roder… - Journal of …, 2013 - jneurosci.org
Schizophrenia is thought to result from interactions between susceptible genotypes and
environmental risk factors. DISC1 is an important gene for schizophrenia and mood …

Is there an association between peripheral immune markers and structural/functional neuroimaging findings?

T Frodl, F Amico - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Objectives There is mounting evidence that inflammatory processes play a key role in
emotional as well as cognitive dysfunctions. In this context, research employing magnetic …