Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19

AB Koopmans, MH Braakman, DJ Vinkers… - Translational …, 2021 - nature.com
Extensive migration has led to the necessity of knowledge regarding the treatment of
migrants with different ethnical backgrounds. This is especially relevant for pharmacological …

[HTML][HTML] Mainstreaming genetics and genomics: a systematic review of the barriers and facilitators for nurses and physicians in secondary and tertiary care

S White, C Jacobs, J Phillips - Genetics in Medicine, 2020 - Elsevier
Purpose Genetic and genomic health information increasingly informs routine clinical care
and treatment. This systematic review aimed to identify the barriers and facilitators to …

[HTML][HTML] The composition and capacity of the clinical genetics workforce in high-income countries: a sco** review

N Dragojlovic, K Borle, N Kopac, U Ellis, P Birch… - Genetics in …, 2020 - Elsevier
As genetics becomes increasingly integrated into all areas of health care and the use of
complex genetic tests continues to grow, the clinical genetics workforce will likely face …

Direct-to-consumer genetic testing: an updated systematic review of healthcare professionals' knowledge and views, and ethical and legal concerns

MF Martins, LT Murry, L Telford… - European Journal of …, 2022 - nature.com
Direct-to-consumer genetic testing (DTC-GT) is becoming increasingly widespread. The aim
of this research was to systematically review the literature published on healthcare …

[HTML][HTML] Internet-based direct-to-consumer genetic testing: a systematic review

L Covolo, S Rubinelli, E Ceretti, U Gelatti - Journal of medical Internet …, 2015 - jmir.org
Background Direct-to-consumer genetic tests (DTC-GT) are easily purchased through the
Internet, independent of a physician referral or approval for testing, allowing the retrieval of …

Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait

A Albassam, S Alshammari, G Ouda, S Koshy, A Awad - PloS one, 2018 - journals.plos.org
Background Pharmacogenetics practice has been successfully implemented in many
developed countries to enhance personalized medicine and improve clinical and economic …

Preparing medical specialists to practice genomic medicine: education an essential part of a broader strategy

E Crellin, B McClaren, A Nisselle, S Best, C Gaff… - Frontiers in …, 2019 - frontiersin.org
Develo** a competent workforce will be crucial to realizing the promise of genomic
medicine. The preparedness of medical specialists without specific genetic qualifications to …

Elucidating the diagnostic odyssey of 22q11. 2 deletion syndrome

LD Palmer, NJ Butcher, E Boot… - American Journal of …, 2018 - Wiley Online Library
Clinical molecular testing has been available for 22q11. 2 deletion syndrome (22q11. 2DS)
for over two decades yet under‐recognition and diagnostic delays are common. To …

Antidepressant prescribing in the precision medicine era: a prescriber's primer on pharmacogenetic tools

CA Bousman, M Forbes, M Jayaram, H Eyre… - BMC psychiatry, 2017 - Springer
About half of people who take antidepressants do not respond and many experience
adverse effects. These detrimental outcomes are in part a result of the impact of an …

Genetic testing in the epilepsies—developments and dilemmas

A Poduri, BR Sheidley, S Shostak… - Nature reviews Neurology, 2014 - nature.com
In the past two decades, the number of genes recognized to have a role in the epilepsies
has dramatically increased. The availability of testing for epilepsy-related genes is …