Muscle injury induces strong changes in muscle cells and extracellular matrix. Muscle
regeneration after injury has similarities to muscle development during embryogenesis and …

Pituitary tumor-transforming gene-1 (PTTG1) is overexpressed in a variety of endocrine-
related tumors, especially pituitary, thyroid, breast, ovarian, and uterine tumors, as well as …

Skeletal muscle is able not only to increase its mass as an adaptation to mechanical loading
generated by and imposed upon muscle but also to regenerate after damage, via its intrinsic …

There is increasing recognition that three-dimensional (3D) tissue culture technologies have
many uses within the biomedical sciences beyond the scope of regenerative medicine. One …

There is abundant in vitro, animal and epidemiologic evidence to suggest that the Insulin-
Like Growth Factor (IGF) family is a multi-component network of molecules which is involved …

The ability of a tumor cell population to grow exponentially represents an imbalance
between cellular proliferation and cellular attrition. There is an overwhelming body of …

Dose-dense adjuvant breast cancer chemotherapy is a new treatment strategy that aims to
improve tumour control by using more frequent cytotoxic dosing together with continuous …

2. Introduction.. 3. Skeletal Muscle Damage-Inflammation-Regeneration: A Conspectus 4.
The Inflammatory Cell Responses to Muscle Damage 5. The Cytokine Responses to Muscle …

Prostate cancer shows a strong predilection to spread to the bones. Once prostate tumour
cells are engrafted in the skeleton, curative therapy is no longer possible and palliative …

Cancer-stromal interaction results in the co-evolution of both the cancer cells and the
surrounding host stromal cells. As a consequence of this interaction, cancer cells acquire …