The use of cytotoxic chemotherapy in both advanced and early stage breast cancer has
made significant progress in the last 10 years with several landmark studies identifying clear …

It has been over three decades since anthracyclines took their place as the standard
chemotherapy backbone for breast cancer in the curative setting. Though the efficacy of …

Vascular endothelial growth factor (VEGF)-A is overexpressed in most malignant and
premalignant breast lesions. VEGF-A can be visualized noninvasively with PET imaging and …

Objectives The purpose of this study was to investigate the potential correlation between
lactate dehydrogenase A (LDHA) and AMP-activated protein kinase (AMPK) and their …

HER2 overexpression or amplification has been shown to be associated with a poor
prognostic effect in women with breast cancer. At least eight analyses based on randomized …

Vascular endothelial growth factor (VEGF) is important in breast carcinogenesis. However,
whether the effect of VEGF expression on survival varies with intrinsic subtypes of breast …

Taxanes are among the most widely used chemotherapy agents for advanced breast
cancer. Results are now available from 21 trials that randomly allocated nearly 36,000 …

To determine the significance of (Cyclooxygenase 2) COX2 for clinical outcome in breast
cancer, we analyzed the correlation between COX2 overexpression and survival in 687 …

The key to optimising our approach in early breast cancer is to individualise care. Each
patient has a tumour with innate features that dictate their chance of relapse and their …

Background Amplification and/or overexpression of the HER2/neu gene is associated with a
poor prognosis in breast cancer. Many studies have suggested that this gene may be …