Effect of alcohol use on the adolescent brain and behavior

B Lees, LR Meredith, AE Kirkland, BE Bryant… - Pharmacology …, 2020 - Elsevier
Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Effects of adolescent alcohol consumption on the brain and behaviour

LP Spear - Nature Reviews Neuroscience, 2018 - nature.com
Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration

K Gawel, E Gibula, M Marszalek-Grabska… - Naunyn-Schmiedeberg's …, 2019 - Springer
Among the methods valuable for assessing spatial learning and memory impairments in
rodents, the Barnes maze (BM) task deserves special attention. It is based on the …

Adolescent alcohol exposure persistently impacts adult neurobiology and behavior

FT Crews, RP Vetreno, MA Broadwater… - Pharmacological …, 2016 - Elsevier
Adolescence is a developmental period when physical and cognitive abilities are optimized,
when social skills are consolidated, and when sexuality, adolescent behaviors, and frontal …

Alcohol-associated tissue injury: current views on pathophysiological mechanisms

L Simon, FM Souza-Smith… - Annual review of …, 2022 - annualreviews.org
At-risk alcohol use is a major contributor to the global health care burden and leads to
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …

[HTML][HTML] Alcohol's effects on the brain: neuroimaging results in humans and animal models

NM Zahr, A Pfefferbaum - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Mechanisms of persistent neurobiological changes following adolescent alcohol exposure: NADIA consortium findings

FT Crews, DL Robinson, LJ Chandler… - Alcoholism: clinical …, 2019 - Wiley Online Library
The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

[HTML][HTML] The brain interstitial system: Anatomy, modeling, in vivo measurement, and applications

Y Lei, H Han, F Yuan, A Javeed, Y Zhao - Progress in neurobiology, 2017 - Elsevier
Although neurons attract the most attention in neurobiology, our current knowledge of neural
circuit can only partially explain the neurological and psychiatric conditions of the brain …

[HTML][HTML] Neuroimmune function and the consequences of alcohol exposure

FT Crews, DK Sarkar, L Qin, J Zou… - Alcohol research …, 2015 - ncbi.nlm.nih.gov
Induction of neuroimmune genes by binge drinking increases neuronal excitability and
oxidative stress, contributing to the neurobiology of alcohol dependence and causing …

Toll-like receptor signaling and stages of addiction

FT Crews, TJ Walter, LG Coleman, RP Vetreno - Psychopharmacology, 2017 - Springer
Abstract Background Athina Markou and her colleagues discovered persistent changes in
adult behavior following adolescent exposure to ethanol or nicotine consistent with …