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Metal sensing by DNA
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …
past two decades, many DNA-based metal sensors have emerged. While the main …
Discovery and biosensing applications of diverse RNA-cleaving DNAzymes
Conspectus DNA-based enzymes, or DNAzymes, are not known to exist in Nature but can
be isolated from random-sequence DNA pools using test tube selection techniques. Since …
be isolated from random-sequence DNA pools using test tube selection techniques. Since …
Graphene–DNAzyme Based Biosensor for Amplified Fluorescence “Turn-On” Detection of Pb2+ with a High Selectivity
XH Zhao, RM Kong, XB Zhang, HM Meng… - Analytical …, 2011 - ACS Publications
On the basis of the remarkable difference in affinity of graphene (GO) with ssDNA containing
a different number of bases in length, we for the first time report a GO–DNAzyme based …
a different number of bases in length, we for the first time report a GO–DNAzyme based …
A highly selective lead sensor based on a classic lead DNAzyme
A catalytic beacon sensor for Pb2+ has been developed based on the first DNAzyme
discovered in the field, and such a sensor has shown a much higher metal ion selectivity (40 …
discovered in the field, and such a sensor has shown a much higher metal ion selectivity (40 …
DNA catalysis: the chemical repertoire of DNAzymes
M Hollenstein - Molecules, 2015 - mdpi.com
Deoxyribozymes or DNAzymes are single-stranded catalytic DNA molecules that are
obtained by combinatorial in vitro selection methods. Initially conceived to function as gene …
obtained by combinatorial in vitro selection methods. Initially conceived to function as gene …
Biologically inspired synthetic enzymes made from DNA
K Schlosser, Y Li - Chemistry & biology, 2009 - cell.com
In cells, DNA typically consists of two antiparallel strands arranged in a double-helical
structure, which is central to its fundamental role in storing and transmitting genetic …
structure, which is central to its fundamental role in storing and transmitting genetic …
DNA-catalyzed sequence-specific hydrolysis of DNA
Deoxyribozymes (DNA catalysts) have been reported for cleavage of RNA phosphodiester
linkages, but cleaving peptide or DNA phosphodiester linkages is much more challenging …
linkages, but cleaving peptide or DNA phosphodiester linkages is much more challenging …
A versatile endoribonuclease mimic made of DNA: characteristics and applications of the 8–17 RNA‐cleaving DNAzyme
K Schlosser, Y Li - ChemBioChem, 2010 - Wiley Online Library
Enzymes play a crucial role in all living organisms by accelerating the rates of a myriad of
biochemical reactions that are necessary to sustain life. Although the vast majority of known …
biochemical reactions that are necessary to sustain life. Although the vast majority of known …
A high-fidelity DNAzyme-assisted CRISPR/Cas13a system with single-nucleotide resolved specificity
Y Wu, R **, Y Chang, M Liu - Chemical Science, 2024 - pubs.rsc.org
A CRISPR/Cas system represents an innovative tool for develo** a new-generation
biosensing and diagnostic strategy. However, the off-target issue (ie, mistaken cleavage of …
biosensing and diagnostic strategy. However, the off-target issue (ie, mistaken cleavage of …
Sensing Parts-per-Trillion Cd2+, Hg2+, and Pb2+ Collectively and Individually Using Phosphorothioate DNAzymes
Cadmium, mercury, and lead are collectively banned by many countries and regions in
electronic devices due to their extremely high toxicity. To date, no sensing method can …
electronic devices due to their extremely high toxicity. To date, no sensing method can …