This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor, which is
activated by a large group of environmental pollutants including polycyclic aromatic …

Most effects of exposure to halogenated and polycyclic aromatic hydrocarbons are mediated
by the aryl hydrocarbon receptor (AHR). It has long been recognized that the AHR is a …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and member of
the bHLH/PAS (basic Helix-Loop-Helix/Per-Arnt-Sim) family of chemosensors and …

Previous studies have demonstrated that 2, 3, 7, 8 tetracholorodibenzo-p-dioxin (TCDD)
mimics epidermal growth factor receptor (EGFR) signaling in the MCF-10A human mammary …

The dioxin/aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription
factor regulating transcription of a battery of genes encoding enzymes involved in drug …

Connexins are subunits of gap junction channels, which mediate the direct transfer of ions,
second messenger molecules and other metabolites between contacting cells. Gap …

Compiling significant advances from more than a decade of research, this text presents
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …

Epidemiologic studies indicate that environmental (smoking) and dietary factors (high fat)
contribute to carcinogenesis in many organ systems. The aim of our study was to test the …

Abstract The contaminant 2, 3, 7, 8‐tetrachlorodibenzo‐p‐dioxin (TCDD) is a prototype
compound of a whole class of halogenated aromatic hydrocarbons termed 'dioxinlike' …