Lipid droplets in inflammation and cancer

PT Bozza, JPB Viola - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2010 - Elsevier
Accumulation of lipid droplets (also known as lipid bodies or adiposomes) within leukocytes,
epithelial cells, hepatocytes and other non-adipocytic cells is a frequently observed …

Leukocyte lipid bodies—biogenesis and functions in inflammation

PT Bozza, KG Magalhães, PF Weller - … (BBA)-Molecular and Cell Biology of …, 2009 - Elsevier
Lipid body accumulation within leukocytes is a common feature in both clinical and
experimental infectious, neoplasic and other inflammatory conditions. Here, we will review …

Liver fibrosis in mice induced by carbon tetrachloride and its reversion by luteolin

R Domitrović, H Jakovac, J Tomac, I Šain - Toxicology and applied …, 2009 - Elsevier
Hepatic fibrosis is effusive wound healing process in which excessive connective tissue
builds up in the liver. Because specific treatments to stop progressive fibrosis of the liver are …

Commitment of bone marrow cells to hepatic stellate cells in mouse

S Baba, H Fujii, T Hirose, K Yasuchika, H Azuma… - Journal of …, 2004 - Elsevier
Background/Aims: Recently, several cells found within the liver have been reported to derive
from bone marrow (BM). This study sought to examine the commitment of BM cells to hepatic …

Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?

J Herrmann, AM Gressner… - Journal of cellular and …, 2007 - Wiley Online Library
• Introduction• General aspects of immortal HSC• Immortalized murine HSC lines‐GRX‐
SV68 c‐IS‐A640‐IS‐M1–4HSC‐A7• Immortalized rat HSC lines‐HSC‐T6‐NFSC, CFSC and …

Leukocyte lipid bodies regulation and function: contribution to allergy and host defense

PT Bozza, RCN Melo, C Bandeira-Melo - Pharmacology & therapeutics, 2007 - Elsevier
Lipid bodies are lipid-rich organelles found in the cytoplasm of a variety of cells, including
leukocytes. Lipid body morphology, its ability to interact with other organelles and its …

Monocyte chemoattractant protein-1/CC chemokine ligand 2 controls microtubule-driven biogenesis and leukotriene B4-synthesizing function of macrophage lipid …

P Pacheco, A Vieira-de-Abreu, RN Gomes… - The Journal of …, 2007 - journals.aai.org
Lipid bodies (also known as lipid droplets) are emerging as inflammatory organelles with
roles in the innate immune response to infections and inflammatory processes. In this study …

Liver fibrosis in vitro: cell culture models and precision-cut liver slices

M Van de Bovenkamp, GMM Groothuis, DKF Meijer… - Toxicology in vitro, 2007 - Elsevier
Chronic liver injury of various etiologies can cause liver fibrosis, which is characterized by
the progressive accumulation of connective tissue in the liver. As no effective treatment for …

The ameliorative effects of fucoidan in thioacetaide-induced liver injury in mice

MY Tsai, WC Yang, CF Lin, CM Wang, HY Liu, CS Lin… - Molecules, 2021 - mdpi.com
Liver disorders have been recognized as one major health concern. Fucoidan, a sulfated
polysaccharide extracted from the brown seaweed Fucus serratus, has previously been …

The value of α‐SMA in the evaluation of hepatic fibrosis severity in hepatitis B infection and cirrhosis development: a histopathological and immunohistochemical …

N Akpolat, S Yahsi, A Godekmerdan, M Yalniz… - …, 2005 - Wiley Online Library
Aims: To investigate the value of α‐smooth muscle actin (α‐SMA), an indicator of stellate cell
activation, in predicting fibrosis in chronic hepatitis B (CHB) patients. Methods and results …