The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2
P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …
Evolution of enhanced innate immune evasion by SARS-CoV-2
The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance
human-to-human transmission,. Although much effort has focused on the characterization of …
human-to-human transmission,. Although much effort has focused on the characterization of …
COVID-19 vaccines: The status and perspectives in delivery points of view
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
SARS-CoV-2 spike D614G change enhances replication and transmission
During the evolution of SARS-CoV-2 in humans, a D614G substitution in the spike
glycoprotein (S) has emerged; virus containing this substitution has become the …
glycoprotein (S) has emerged; virus containing this substitution has become the …
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants
AK Reuschl, LG Thorne, MVX Whelan… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) human adaptation resulted
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …
in distinct lineages with enhanced transmissibility called variants of concern (VOCs) …
COVID-19 vaccine development and a potential nanomaterial path forward
MD Shin, S Shukla, YH Chung, V Beiss… - Nature …, 2020 - nature.com
The COVID-19 pandemic has infected millions of people with no clear signs of abatement
owing to the high prevalence, long incubation period and lack of established treatments or …
owing to the high prevalence, long incubation period and lack of established treatments or …
[HTML][HTML] SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …
A prenylated dsRNA sensor protects against severe COVID-19
INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …
invading pathogens. By initiating a signaling cascade that stimulates the expression of …
COVID‐19 epidemic: disease characteristics in children
J She, L Liu, W Liu - Journal of medical virology, 2020 - Wiley Online Library
In mid‐December 2019, a disease caused by infection with severe acute respiratory
syndrome coronavirus‐2, which began in Wuhan, China, has spread throughout the country …
syndrome coronavirus‐2, which began in Wuhan, China, has spread throughout the country …