Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Identification, evaluation, and management of children with autism spectrum disorder

SL Hyman, SE Levy, SM Myers, DZ Kuo, S Apkon… - …, 2020 - publications.aap.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with reported
prevalence in the United States of 1 in 59 children (approximately 1.7%). Core deficits are …

Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis

A Jourdon, F Wu, J Mariani, D Capauto, S Norton… - Nature …, 2023 - nature.com
Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear
how convergent biological processes in affected individuals may give rise to symptoms …

[HTML][HTML] Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation

H Hodges, C Fealko, N Soares - Translational pediatrics, 2020 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits
in social communication and the presence of restricted interests and repetitive behaviors …

Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy

L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian… - Nature …, 2018 - nature.com
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …

Imaging structural and functional brain development in early childhood

JH Gilmore, RC Knickmeyer, W Gao - Nature Reviews Neuroscience, 2018 - nature.com
In humans, the period from term birth to∼ 2 years of age is characterized by rapid and
dynamic brain development and plays an important role in cognitive development and risk of …

Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits

E Kelly, F Meng, H Fujita, F Morgado, Y Kazemi… - Nature …, 2020 - nature.com
Cerebellar dysfunction has been demonstrated in autism spectrum disorders (ASDs);
however, the circuits underlying cerebellar contributions to ASD-relevant behaviors remain …

Developmental mechanisms underlying the evolution of human cortical circuits

P Vanderhaeghen, F Polleux - Nature Reviews Neuroscience, 2023 - nature.com
The brain of modern humans has evolved remarkable computational abilities that enable
higher cognitive functions. These capacities are tightly linked to an increase in the size and …

[LIVRE][B] Autism: A new introduction to psychological theory and current debate

S Fletcher-Watson, F Happé - 2019 - taylorfrancis.com
Based on Francesca Happé's best-selling textbook, Autism: An Introduction to Psychological
Theory, this completely new edition provides a concise overview of contemporary …