The dynamic regulation of chromatin accessibility is one of the prominent characteristics of
eukaryotic genome. The inaccessible regions are mainly located in heterochromatin, which …

Histone proteins are the building blocks of chromatin, and function by wrap** DNA into
complex structures that control gene expression. Histone proteins are regulated by post …

Chromatin architecture governs DNA accessibility and gene expression. Thus, any
perturbations to chromatin can significantly alter gene expression programs and promote …

Histone variants are the paralogs of core histones (H2A, H2B, H3 and H4). They are stably
expressed throughout the cell cycle in a replication-independent fashion and are capable of …

SUMMARY A cell's ability to respond and adapt to environmental stimuli relies in part on
transcriptional programs controlled by histone proteins. Histones affect transcription through …

Histones bind directly to DNA and play a role in regulating gene expression mediated by
chromatin structure. DNA sequences of these histone genes are quite similar, which has …

The nucleosome is the fundamental unit of the genome that organizes DNA and is made of
four histone proteins: H2A, H2B, H3, and H4. Regulation of histone proteins affects gene …

The evolving field of neuroepigenetics provides important insights into the molecular
foundations of brain function. Novel sequencing technologies have identified patient-specific …