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Sonogenetics for monitoring and modulating biomolecular function by ultrasound
Ultrasound technology, synergistically harnessed with genetic engineering and chemistry
concepts, has started to open the gateway to the remarkable realm of sonogenetics—a …
concepts, has started to open the gateway to the remarkable realm of sonogenetics—a …
Exploiting the mechanical effects of ultrasound for noninvasive therapy
MA O'Reilly - Science, 2024 - science.org
Focused ultrasound is a platform technology capable of eliciting a wide range of biological
responses with high spatial precision deep within the body. Although focused ultrasound is …
responses with high spatial precision deep within the body. Although focused ultrasound is …
Nanobubble-actuated ultrasound neuromodulation for selectively sha** behavior in mice
Ultrasound is an acoustic wave which can noninvasively penetrate the skull to deep brain
regions, enabling neuromodulation. However, conventional ultrasound's spatial resolution is …
regions, enabling neuromodulation. However, conventional ultrasound's spatial resolution is …
Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology
Focused ultrasound can non-invasively modulate neural activity, but whether effective
stimulation parameters generalize across brain regions and cell types remains unknown …
stimulation parameters generalize across brain regions and cell types remains unknown …
Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow
Hyperemia in response to neural activity is essential for brain health. A hyperemic response
delivers O2 and nutrients, clears metabolic waste, and concomitantly exposes …
delivers O2 and nutrients, clears metabolic waste, and concomitantly exposes …
[HTML][HTML] Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system
B Zong, F Yu, X Zhang, Y Pang, W Zhao, P Sun… - Ageing Research …, 2023 - Elsevier
Since the discovery of the mechanosensitive Piezo1 channel in 2010, there has been a
significant amount of research conducted to explore its regulatory role in the physiology and …
significant amount of research conducted to explore its regulatory role in the physiology and …
Acoustic virtual 3D scaffold for direct-interacting tumor organoid–immune cell coculture systems
H Shan, M Chen, S Zhao, X Wei, M Zheng, Y Li… - Science …, 2024 - science.org
Three-dimensional (3D) cell culture has revolutionized life sciences, particularly in organoid
technologies. Traditional bioscaffold materials, however, complicate the detachment of …
technologies. Traditional bioscaffold materials, however, complicate the detachment of …
Low-intensity focused ultrasound for human neuromodulation
Low-intensity focused ultrasound (LIFU) is a potentially transformative form of human non-
invasive neuromodulation that provides millimetre-sized focal volumes combined with …
invasive neuromodulation that provides millimetre-sized focal volumes combined with …
[HTML][HTML] The relationship between parameters and effects in transcranial ultrasonic stimulation.
Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human
neuromodulation, with a pressing need to establish protocols that maximise …
neuromodulation, with a pressing need to establish protocols that maximise …
[HTML][HTML] Transcranial focused ultrasound stimulation in the infralimbic cortex facilitates extinction of conditioned fear in rats
Transcranial focused ultrasound (tFUS) neuromodulation emerges as a promising non-
invasive approach for improving neurological conditions. Extinction of conditioned fear has …
invasive approach for improving neurological conditions. Extinction of conditioned fear has …