[HTML][HTML] Polymeric micellar systems—A special emphasis on “smart” drug delivery

I Negut, B Bita - Pharmaceutics, 2023 - mdpi.com
Concurrent developments in anticancer nanotechnological treatments have been observed
as the burden of cancer increases every year. The 21st century has seen a transformation in …

Impact of NQO1 dysregulation in CNS disorders

L Yuhan, M Khaleghi Ghadiri, A Gorji - Journal of Translational Medicine, 2024 - Springer
Abstract NAD (P) H Quinone Dehydrogenase 1 (NQO1) plays a pivotal role in the regulation
of neuronal function and synaptic plasticity, cellular adaptation to oxidative stress …

Bioactive peptides from skipjack tuna cardiac arterial bulbs (II): Protective function on UVB-irradiated HaCaT cells through antioxidant and anti-apoptotic mechanisms

J Kong, XM Hu, WW Cai, YM Wang, CF Chi, B Wang - Marine Drugs, 2023 - mdpi.com
The aim of this study was to investigate the protective function and mechanism of TCP3
(PKK), TCP6 (YEGGD) and TCP9 (GPGLM) from skipjack tuna cardiac arterial bulbs on skin …

Role of STAT3 in the initiation, progression, proliferation and metastasis of breast cancer and strategies to deliver JAK and STAT3 inhibitors

YH Dinakar, H Kumar, SL Mudavath, R Jain, R Ajmeer… - Life Sciences, 2022 - Elsevier
Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …

[HTML][HTML] Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in …

KR Paudel, N Panth, B Manandhar, SK Singh, G Gupta… - Antioxidants, 2022 - mdpi.com
Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary
disease. Numerous toxicants present in cigarette smoke are known to induce oxidative …

Dual role of Nrf2 in cancer: molecular mechanisms, cellular functions and therapeutic interventions

M Poornashree, H Kumar, R Ajmeer, R Jain… - Molecular Biology …, 2023 - Springer
Background Nrf2 regulates oxidative stress, which is essential for cellular function.
Fundamental initiation of Nrf2 in many malignancies increases prosurvival genes & …

Zerumbone liquid crystalline nanoparticles protect against oxidative stress, inflammation and senescence induced by cigarette smoke extract in vitro

KR Paudel, DD Clarence, N Panth… - Naunyn-schmiedeberg's …, 2024 - Springer
The purpose of this study was to evaluate the potential of zerumbone-loaded liquid
crystalline nanoparticles (ZER-LCNs) in the protection of broncho-epithelial cells and …

[HTML][HTML] Perfluorooctanoic acid (PFOA) and hexafluoropropylene oxide-dimer acid (GenX): Hepatic stress and bile acid metabolism with different pathways

HJ Yoo, MC Pyo, KH Rhee, JM Lim, SA Yang… - Ecotoxicology and …, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) and perfluoroalkyl ether carboxylic acids
(PFECAs) are organic chemicals that are widely used in the manufacture of a wide range of …

Maternal supplementation with n-3 fatty acids affects placental lipid metabolism, inflammation, oxidative stress, the endocannabinoid system, and the neonate cytokine …

P dos Santos Silva, G Kra, Y Butenko… - Journal of Animal …, 2024 - Springer
Background The placenta plays a crucial role in supporting and influencing fetal
development. We compared the effects of prepartum supplementation with omega-3 (n-3) …

NQO1 Triggers Neutrophil Recruitment and NET Formation to Drive Lung Metastasis of Invasive Breast Cancer

X Wang, Y Qu, Q Xu, Z Jiang, H Wang, B Lin… - Cancer …, 2024 - aacrjournals.org
Metastasis to the lungs is a leading cause of death for patients with breast cancer. Therefore,
effective therapies are urgently needed to prevent and treat lung metastasis. In this study, we …