Oxidative stress and advanced lipoxidation and glycation end products (ALEs and AGEs) in aging and age‐related diseases
NT Moldogazieva, IM Mokhosoev… - Oxidative medicine …, 2019 - Wiley Online Library
Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living
organisms and is denoted as a persistent condition of an imbalance between the generation …
organisms and is denoted as a persistent condition of an imbalance between the generation …
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …
may increase the risk for heart failure development. This risk evolves from functional and …
Biochemical and clinical impact of organic uremic retention solutes: a comprehensive update
R Vanholder, A Pletinck, E Schepers, G Glorieux - Toxins, 2018 - mdpi.com
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …
individual uremic retention solutes and groups of solutes is summarized. We classified these …
[HTML][HTML] Dietary advanced glycation end products and their relevance for human health
Due to their bioactivity and harmful potential, advanced glycation end products (AGEs) are
discussed to affect human health. AGEs are compounds formed endogenously in the human …
discussed to affect human health. AGEs are compounds formed endogenously in the human …
Retracted: chronic inflammation: accelerator of biological aging
B Fougère, E Boulanger, F Nourhashémi… - The Journals of …, 2017 - academic.oup.com
Biological aging is characterized by a chronic low-grade inflammation level. This chronic
phenomenon has been named “inflamm-aging” and is a highly significant risk factor for …
phenomenon has been named “inflamm-aging” and is a highly significant risk factor for …
Gut-derived protein-bound uremic toxins
Chronic kidney disease (CKD) afflicts more than 500 million people worldwide and is one of
the fastest growing global causes of mortality. When glomerular filtration rate begins to fall …
the fastest growing global causes of mortality. When glomerular filtration rate begins to fall …
Uremic toxicity of advanced glycation end products in CKD
AEM Stinghen, ZA Massy, H Vlassara… - Journal of the …, 2016 - journals.lww.com
Advanced glycation end products (AGEs), a heterogeneous group of compounds formed by
nonenzymatic glycation reactions between reducing sugars and amino acids, lipids, or DNA …
nonenzymatic glycation reactions between reducing sugars and amino acids, lipids, or DNA …
The receptor for advanced glycation end-products (RAGE) is an important pattern recognition receptor (PRR) for inflammaging
The receptor for advanced glycation end-products (RAGE) was initially characterized and
named for its ability to bind to advanced glycation end-products (AGEs) that form upon the …
named for its ability to bind to advanced glycation end-products (AGEs) that form upon the …
Protein carbamylation is a hallmark of aging
L Gorisse, C Pietrement, V Vuiblet… - Proceedings of the …, 2016 - National Acad Sciences
Aging is a progressive process determined by genetic and acquired factors. Among the latter
are the chemical reactions referred to as nonenzymatic posttranslational modifications …
are the chemical reactions referred to as nonenzymatic posttranslational modifications …
Advanced glycation end-products (AGEs) in foods and their detecting techniques and methods: A review
Q Wei, T Liu, DW Sun - Trends in Food Science & Technology, 2018 - Elsevier
Background Advanced glycation end-products (AGEs) are a sort of complex products formed
by the Maillard reaction between the carbonyls of reducing sugars and the free amino …
by the Maillard reaction between the carbonyls of reducing sugars and the free amino …