Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …

Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …

Exposure to cadmium (Cd), an environmental heavy metal contaminant, is a serious threat to
global health that increases the burden of liver diseases. Autophagy and apoptosis are …

The proportion of advanced age patients undergoing surgical procedures is on the rise
owing to advancements in surgical and anesthesia technologies as well as an overall aging …

Abstract Ethnopharmacological relevance Fructus Gardeniae, with the effects of discharging
fire, eliminating vexation, reducing fever and causing diuresis, and cooling blood to remove …

The endoplasmic reticulum (ER) plays a vital function in maintaining cellular homeostasis.
Endoplasmic reticulum stress (ERS) can trigger various modes of cell death by activating the …

Diabetic wounds are characterized by delayed and incomplete healing. As one of the most
common complications of diabetes, diabetic wounds can be fatal in some cases …

Although a number of mood-stabilising atypical antipsychotics and antidepressants
modulate serotonin type 7 receptor (5-HT7), the detailed contributions of 5-HT7 function to …

Diabetic foot ulcers (DFUs) are a microvascular complication that affects almost 21% of the
diabetic population. DFUs are characterized by lower limb abnormalities, chronic …

Osteosarcomas are malignant bone tumors that typically originate in the epiphyses of the
long bones of the extremities in adolescents. Asiatic acid has been reported to possess anti …