Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development

H Yu, O Alkhamis, J Canoura, Y Liu… - Angewandte Chemie …, 2021 - Wiley Online Library
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

From reads to insight: a hitchhiker's guide to ATAC-seq data analysis

F Yan, DR Powell, DJ Curtis, NC Wong - Genome biology, 2020 - Springer
Abstract Assay of Transposase Accessible Chromatin sequencing (ATAC-seq) is widely
used in studying chromatin biology, but a comprehensive review of the analysis tools has …

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection

DG Augusto, LD Murdolo, DSM Chatzileontiadou… - Nature, 2023 - nature.com
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …

Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

P Jacob, NH Kim, F Wu, F El-Kasmi, Y Chi, WG Walton… - Science, 2021 - science.org
Plant nucleotide-binding leucine-rich repeat receptors (NLRs) regulate immunity and cell
death. In Arabidopsis, a subfamily of “helper” NLRs is required by many “sensor” NLRs …

Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease

M Otero-Garcia, SU Mahajani, D Wakhloo, W Tang… - Neuron, 2022 - cell.com
Tau aggregation in neurofibrillary tangles (NFTs) is closely associated with
neurodegeneration and cognitive decline in Alzheimer's disease (AD). However, the …

From clustering to clustering ensemble selection: A review

K Golalipour, E Akbari, SS Hamidi, M Lee… - … Applications of Artificial …, 2021 - Elsevier
Clustering, as an unsupervised learning, is aimed at discovering the natural grou**s of a
set of patterns, points, or objects. In clustering algorithms, a significant problem is the …

[HTML][HTML] Acetylation of cytidine in mRNA promotes translation efficiency

D Arango, D Sturgill, N Alhusaini, AA Dillman, TJ Sweet… - Cell, 2018 - cell.com
Generation of the" epitranscriptome" through post-transcriptional ribonucleoside
modification embeds a layer of regulatory complexity into RNA structure and function. Here …

AlgPred 2.0: an improved method for predicting allergenic proteins and map** of IgE epitopes

N Sharma, S Patiyal, A Dhall, A Pande… - Briefings in …, 2021 - academic.oup.com
AlgPred 2.0 is a web server developed for predicting allergenic proteins and allergenic
regions in a protein. It is an updated version of AlgPred developed in 2006. The dataset …

A high-resolution protein architecture of the budding yeast genome

MJ Rossi, PK Kuntala, WKM Lai, N Yamada, N Badjatia… - Nature, 2021 - nature.com
The genome-wide architecture of chromatin-associated proteins that maintains chromosome
integrity and gene regulation is not well defined. Here we use chromatin …

Disentangling direct from indirect relationships in association networks

N **ao, A Zhou, ML Kempher… - Proceedings of the …, 2022 - National Acad Sciences
Networks are vital tools for understanding and modeling interactions in complex systems in
science and engineering, and direct and indirect interactions are pervasive in all types of …