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Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …
to specific molecules with high affinity, and offer a number of advantages relative to …
From reads to insight: a hitchhiker's guide to ATAC-seq data analysis
Abstract Assay of Transposase Accessible Chromatin sequencing (ATAC-seq) is widely
used in studying chromatin biology, but a comprehensive review of the analysis tools has …
used in studying chromatin biology, but a comprehensive review of the analysis tools has …
A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
remain asymptomatic,,–. Although most global efforts have focused on severe illness in …
Nitrogen-fixing organelle in a marine alga
Symbiotic interactions were key to the evolution of chloroplast and mitochondria organelles,
which mediate carbon and energy metabolism in eukaryotes. Biological nitrogen fixation, the …
which mediate carbon and energy metabolism in eukaryotes. Biological nitrogen fixation, the …
Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels
Plant nucleotide-binding leucine-rich repeat receptors (NLRs) regulate immunity and cell
death. In Arabidopsis, a subfamily of “helper” NLRs is required by many “sensor” NLRs …
death. In Arabidopsis, a subfamily of “helper” NLRs is required by many “sensor” NLRs …
[HTML][HTML] Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease
Tau aggregation in neurofibrillary tangles (NFTs) is closely associated with
neurodegeneration and cognitive decline in Alzheimer's disease (AD). However, the …
neurodegeneration and cognitive decline in Alzheimer's disease (AD). However, the …
[HTML][HTML] Acetylation of cytidine in mRNA promotes translation efficiency
Generation of the" epitranscriptome" through post-transcriptional ribonucleoside
modification embeds a layer of regulatory complexity into RNA structure and function. Here …
modification embeds a layer of regulatory complexity into RNA structure and function. Here …
A high-resolution protein architecture of the budding yeast genome
The genome-wide architecture of chromatin-associated proteins that maintains chromosome
integrity and gene regulation is not well defined. Here we use chromatin …
integrity and gene regulation is not well defined. Here we use chromatin …
From clustering to clustering ensemble selection: A review
Clustering, as an unsupervised learning, is aimed at discovering the natural grou**s of a
set of patterns, points, or objects. In clustering algorithms, a significant problem is the …
set of patterns, points, or objects. In clustering algorithms, a significant problem is the …
AlgPred 2.0: an improved method for predicting allergenic proteins and map** of IgE epitopes
AlgPred 2.0 is a web server developed for predicting allergenic proteins and allergenic
regions in a protein. It is an updated version of AlgPred developed in 2006. The dataset …
regions in a protein. It is an updated version of AlgPred developed in 2006. The dataset …